Cat: PAX2000-11075

Recombinant Human RTP1 Protein,GST

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关键信息

  • 基因名

    RTP1

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    RTP1; Z3CXXC1; Receptor-transporting protein 1; 3CxxC-type zinc finger protein 1

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    GST-tag at N-terminal

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P59025

  • 表达区间

    113-202  aa

  • 氨基酸序列

    NIEGLVDNLITSLREQCYGERGGQYRIHVASRQDNRRHRGEFCEACQEGIVHWKPSEKLLEEEATTYTFSRAPSPTKSQDQTGSGWNFCS

  • 分子量

    35.64 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

RTP1 (Receptor Transporting Protein 1) is a crucial protein involved in the intracellular transport and functional expression of G protein-coupled receptors (GPCRs), which are key players in various physiological processes and represent significant drug targets. Research into RTP1 has gained traction due to its potential role in modulating the trafficking of specific GPCRs to the cell surface, thus influencing signaling pathways linked to diverse biological functions, including sensory perception, immune responses, and neurological functions. Abnormalities in RTP1 expression or function may contribute to the pathogenesis of various diseases, including cancers and neurological disorders. Recent studies have focused on characterizing the structural and functional aspects of RTP1, elucidating its interaction with different GPCRs, and understanding its regulatory mechanisms in receptor transport. This research is pivotal, as it could pave the way for novel therapeutic strategies targeting GPCRs more effectively by manipulating their transport and expression dynamics. Consequently, the investigation of RTP1 not only enhances our understanding of GPCR biology but also holds promise for developing innovative approaches in drug discovery and treatment of related diseases. As such, RTP1 stands out as a significant focus of interest in molecular biology and pharmacology, with ongoing studies aimed at unraveling its complex roles in health and disease.

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