| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | RPL10_5_1358 |
| WB Predicted band size | 25 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human RPL10L |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇与RPL10L抗体相关的文献摘要示例(部分为模拟内容，实际文献需根据数据库检索确认)：
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1. **文献名称**: "RPL10L is required for male meiotic division by compensating for RPL10 during mouse spermatogenesis"
**作者**: Wang Y, et al.
**摘要**: 本研究利用RPL10L特异性抗体，通过免疫荧光和Western blot技术，揭示了RPL10L在小鼠精子发生中的关键作用。实验表明，RPL10L在减数分裂阶段补偿其同源蛋白RPL10的功能，敲除RPL10L导致精子形成缺陷和不育。
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2. **文献名称**: "Aberrant expression of RPL10L in hepatocellular carcinoma correlates with poor prognosis"
**作者**: Li X, et al.
**摘要**: 通过免疫组化(使用RPL10L多克隆抗体)分析肝癌组织样本，发现RPL10L在癌组织中显著高表达，且与患者生存率负相关。功能实验表明RPL10L通过调控核糖体生物合成促进肝癌细胞增殖。
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3. **文献名称**: "Structural and functional divergence of RPL10L from its somatic paralog RPL10 in mammals"
**作者**: Zhang H, et al.
**摘要**: 本研究利用RPL10L特异性抗体进行亚细胞定位和互作蛋白筛选，发现RPL10L在生殖细胞中特异性表达，并与减数分裂特异性核糖体复合物结合，其功能无法被体细胞同源蛋白RPL10替代。
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**注**：以上文献为示例性质，实际文献需通过PubMed、Google Scholar等平台以关键词“RPL10L antibody”或“RPL10L function”检索确认。
The RPL10L (Ribosomal Protein L10-like) antibody is a tool used to study the RPL10L protein, a member of the ribosomal protein L10E family. RPL10L shares high homology with RPL10. a component of the 60S ribosomal subunit involved in protein synthesis. Unlike RPL10. which is ubiquitously expressed, RPL10L is testis-specific and plays a critical role in spermatogenesis. It localizes to mitochondrial ribosomes in germ cells, suggesting a specialized function in mitochondrial translation during sperm development. Studies link RPL10L mutations or dysregulation to male infertility, as its absence disrupts sperm maturation and mitochondrial function.
The RPL10L antibody is essential for detecting and quantifying RPL10L expression in research models. It aids in investigating its tissue-specific expression patterns, subcellular localization, and interactions within mitochondrial ribosomes. Applications include Western blotting, immunohistochemistry, and immunofluorescence in testicular tissues or germ cell lines. Commercial RPL10L antibodies are typically raised in rabbits or mice, with validation in human, mouse, or rat samples. Recent research also explores its potential role in cancer biology, particularly in germ cell tumors. Reliable RPL10L antibodies are crucial for advancing reproductive biology and understanding diseases linked to ribosomal dysfunction.
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