Rabbit Polyclonal FUBP3 Antibody

The FUBP3 (Far Upstream Element Binding Protein 3) antibody is a tool used to detect and study the FUBP3 protein, a member of the FUBP family involved in transcriptional and post-transcriptional regulation. FUBP3 binds to single-stranded DNA/RNA and plays roles in processes like mRNA stability, splicing, and translation. While less characterized than FUBP1 (a known MYC oncogene regulator), FUBP3 has been implicated in cellular differentiation, apoptosis, and immune responses. Research links FUBP3 dysregulation to diseases such as leukemia, breast cancer, and neurological disorders, where it may act as a tumor suppressor or promoter depending on context. The antibody is widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to analyze FUBP3 expression patterns in tissues or cell lines. Its applications extend to exploring FUBP3's interaction networks, subcellular localization, and functional roles in disease models. Studies also investigate its potential as a biomarker or therapeutic target. Commercial FUBP3 antibodies are typically developed in hosts like rabbits or mice, validated for specificity across human and model organisms. Ongoing research aims to clarify its dual roles in cancer and normal physiology, emphasizing its context-dependent regulatory mechanisms.