| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| WB Predicted band size | 49 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human TMPRSS11F |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于TMPRSS11F抗体的3篇示例参考文献(内容为模拟虚构，仅供参考)：
1. **文献名称**：*TMPRSS11F facilitates viral entry into human airway epithelial cells via proteolytic activation*
**作者**：Smith, J. et al.
**摘要**：本研究揭示了TMPRSS11F在呼吸道病毒(如流感病毒)感染中的作用，通过其蛋白酶活性切割病毒表面蛋白，促进病毒进入宿主细胞。作者开发了特异性TMPRSS11F抗体，证实其可抑制病毒入侵。
2. **文献名称**：*Characterization of a monoclonal antibody targeting the catalytic domain of TMPRSS11F*
**作者**：Zhang, L. et al.
**摘要**：文章报道了一种针对TMPRSS11F催化结构域的单克隆抗体的开发与验证。该抗体能够阻断TMPRSS11F的酶活性，并在体外模型中降低冠状病毒(如SARS-CoV-2)的感染效率。
3. **文献名称**：*TMPRSS11F expression and function in human lung: Insights from immunohistochemistry using novel antibodies*
**作者**：Johnson, R. et al.
**摘要**：通过新型抗体进行免疫组化分析，发现TMPRSS11F在肺组织上皮细胞中高表达，且与呼吸道黏膜防御和病原体清除相关。研究为TMPRSS11F的生理功能提供了新视角。
(注：以上文献信息为模拟生成，实际研究中请通过PubMed或Google Scholar等平台检索真实文献。)
The TMPRSS11F antibody targets TMPRSS11F (Transmembrane Serine Protease 11F), a member of the type II transmembrane serine protease (TTSP) family. These proteases are characterized by a conserved serine protease domain, a transmembrane anchor, and distinct regulatory regions. TMPRSS11F, also known as HAT-like 5. is expressed in epithelial tissues and is implicated in proteolytic processing of extracellular substrates, potentially influencing cellular signaling, tissue remodeling, and pathogen entry. Its role in physiological and pathological processes remains under investigation, though related TTSPs are known to regulate viral infectivity (e.g., influenza, coronaviruses) and cancer progression via substrate cleavage.
Antibodies against TMPRSS11F are primarily used as research tools to study its expression, localization, and function. They enable detection in immunoassays (e.g., Western blot, immunohistochemistry) and functional studies to explore its interaction with viral glycoproteins or involvement in disease pathways. Emerging evidence suggests TMPRSS11F may contribute to airway inflammation or tumorigenesis, making it a potential biomarker or therapeutic target. However, its precise biological role and clinical relevance require further validation. Commercial TMPRSS11F antibodies are typically validated for specificity in human or model organisms, aiding mechanistic studies in respiratory diseases, oncology, and infectious disease research.
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