| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/30-1/150 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | BXDC1; bA397G5.4 |
| WB Predicted band size | 36 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human RPF2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是模拟生成的关于RPF2抗体的参考文献示例(非真实文献，仅供格式参考)：
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1. **文献名称**: *Development of a High-Affinity RPF2 Antibody for Ribosome Biogenesis Studies*
**作者**: Tanaka, M., et al.
**摘要**: 本研究报道了一种针对人源RPF2蛋白的单克隆抗体的开发，该抗体通过免疫印迹和免疫荧光验证，能特异性识别内源性RPF2.研究证实RPF2在核仁中参与核糖体RNA加工，抗体可用于探究其在癌症细胞增殖中的调控作用。
2. **文献名称**: *RPF2 Antibody-Based Screening Identifies Dysregulated Ribosomal Assembly in Neurodegenerative Models*
**作者**: Chen, L., & Park, J.H.
**摘要**: 利用RPF2多克隆抗体对神经退行性疾病模型进行蛋白质组分析，发现RPF2表达水平与异常核糖体组装相关，提示其可能作为阿尔茨海默病中翻译失调的生物标志物。
3. **文献名称**: *Structural Characterization of RPF2 in Archaea Using a Novel Polyclonal Antibody*
**作者**: Gupta, S., et al.
**摘要**: 通过制备古菌RPF2抗体，结合冷冻电镜技术解析了RPF2在古菌核糖体成熟中的构象变化，揭示了其与RNA解旋酶协同作用的分子机制。
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**注意**：以上文献为模拟生成，实际研究中请通过PubMed、Google Scholar等平台检索真实文献(关键词：RPF2 antibody, ribosomal protein, ribosome biogenesis)。若需具体领域文献，建议补充背景信息以便精准推荐。
The RPF2 antibody is a research tool used to detect RPF2 (Ribosomal Protein Factor 2), a conserved protein involved in ribosome biogenesis. RPF2 plays a critical role in the maturation of the 40S ribosomal subunit by facilitating the processing of 18S rRNA within the nucleolus. It interacts with other ribosome assembly factors, such as RPF1 and BMS1. to ensure proper rRNA folding and ribosomal subunit export to the cytoplasm. Dysregulation of RPF2 is linked to ribosomopathies and cancers, as impaired ribosome assembly can trigger stress responses or uncontrolled cell proliferation.
The RPF2 antibody is widely utilized in molecular biology to study ribosome assembly dynamics, cellular growth mechanisms, and disease pathways. It is commonly applied in techniques like Western blotting, immunofluorescence, and immunoprecipitation to assess RPF2 expression, localization, and interactions. Commercially available antibodies are typically raised against specific epitopes of human RPF2. with validation in model organisms (e.g., yeast, mice) due to its evolutionary conservation. Researchers also employ RPF2 antibodies to explore its potential as a biomarker in cancers or to screen for therapeutic targets in diseases linked to ribosomal dysfunction. Proper controls, such as knockout cell lines, are essential to confirm antibody specificity in experimental settings.
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