Rabbit Polyclonal EFCAB5 Antibody

The EFCAB5 (EF-hand calcium-binding domain-containing protein 5) antibody is a tool used to study the function and expression of the EFCAB5 protein, which belongs to the EF-hand calcium-binding protein family. EFCAB5 is implicated in regulating calcium-mediated signaling pathways and cellular processes, particularly in cilia-related functions. Research suggests its involvement in ciliary motility and structure, potentially impacting conditions like primary ciliary dyskinesia (PCD) or ciliopathies. The protein contains EF-hand motifs, enabling calcium ion binding, which may modulate interactions with other ciliary components such as microtubules or motor proteins. EFCAB5 antibodies are utilized in techniques like Western blotting, immunofluorescence, and immunohistochemistry to localize the protein, assess its expression levels, or investigate its role in cellular mechanisms. Recent studies explore its association with sperm flagella function, respiratory cilia dynamics, and potential links to infertility or respiratory disorders. However, the full scope of EFCAB5's biological roles remains under investigation, necessitating further research to clarify its molecular interactions and therapeutic relevance. These antibodies thus serve as critical reagents for unraveling EFCAB5's contributions to calcium signaling and cilia-related physiology or pathology.