| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/40-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | S28; DBA15 |
| WB Predicted band size | 8 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human RPS28 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于RPS28抗体的3篇参考文献示例(注：文献为虚构示例，仅供参考格式)：
1. **文献名称**: *RPS28 Antibody Characterization and Its Role in Ribosome Biogenesis*
**作者**: Lee, J. et al.
**摘要**: 该研究开发并验证了一种高特异性兔源RPS28多克隆抗体，通过Western blot和免疫荧光证实其在人类细胞系中检测内源性RPS28蛋白的能力，并发现RPS28在核糖体小亚基组装中起关键作用。
2. **文献名称**: *RPS28 as a Potential Biomarker in Hepatocellular Carcinoma*
**作者**: Wang, Y. et al.
**摘要**: 利用RPS28抗体进行免疫组化分析，发现肝癌组织中RPS28蛋白表达显著上调，且与患者预后不良相关，提示其可能作为肝癌诊断的分子标志物。
3. **文献名称**: *Functional Analysis of RPS28 in Zebrafish Development via Antibody-Mediated Knockdown*
**作者**: Chen, H. et al.
**摘要**: 研究通过显微注射RPS28抗体干扰斑马鱼胚胎中RPS28功能，发现其缺失导致胚胎发育异常，证实RPS28在早期脊椎动物发育中不可或缺。
4. **文献名称**: *RPS28 Antibody Reveals Altered Ribosomal Protein Localization in Neurodegenerative Disorders*
**作者**: Müller, S. et al.
**摘要**: 使用RPS28抗体分析阿尔茨海默病模型小鼠脑组织，发现RPS28在神经元中的亚细胞定位异常，可能与蛋白质翻译失调及神经退行性病变相关。
(注：以上文献为示例，实际引用时需查询真实数据库并核实内容。)
The RPS28 antibody is a research tool designed to detect ribosomal protein S28 (RPS28), a component of the 40S subunit of eukaryotic ribosomes. RPS28 plays a critical role in ribosome biogenesis and mRNA translation, contributing to the structural stability of the small ribosomal subunit and ensuring proper protein synthesis. Dysregulation of RPS28 has been linked to ribosomal stress, developmental disorders, and diseases such as Diamond-Blackfan anemia (DBA), a rare bone marrow failure syndrome associated with mutations in ribosomal proteins.
RPS28 antibodies are widely used in molecular and cellular biology to study ribosome assembly, protein translation mechanisms, and disease pathogenesis. They enable the detection and localization of RPS28 in various experimental approaches, including Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and co-immunoprecipitation (Co-IP). These antibodies are typically raised in hosts like rabbits or mice, with validation in knockout cell lines to ensure specificity.
Recent studies also explore RPS28's non-canonical roles, such as its potential involvement in cell cycle regulation and apoptosis. Researchers utilize RPS28 antibodies to investigate its expression patterns in cancer models, where altered ribosomal protein levels may influence tumor progression or therapeutic resistance. As ribosomopathies and cancer-related ribosomal dysfunction gain attention, RPS28 antibodies remain essential for elucidating the molecular interplay between ribosomal integrity and cellular health.
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