Rabbit Polyclonal SHTN1 Antibody

The SHTN1 antibody is a research tool developed to target the SHTN1 protein, a less-characterized molecule implicated in neuronal and synaptic functions. While its exact biological role remains under investigation, preliminary studies suggest SHTN1 may participate in cytoskeletal organization or synaptic vesicle trafficking, potentially influencing neurotransmission and neural plasticity. The antibody was generated using immunogens derived from conserved regions of the SHTN1 protein sequence, often in model organisms like mice or rabbits, yielding either monoclonal or polyclonal variants. It has been validated for applications such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to map SHTN1 expression patterns in brain tissues or cultured neurons. Interest in SHTN1 stems from its hypothesized link to neurodevelopmental disorders and neurodegenerative diseases, though mechanistic insights are scarce. Current research focuses on clarifying its interaction partners, subcellular localization, and potential dysregulation in disease models. However, limited commercial availability and the absence of standardized validation protocols pose challenges for reproducibility. Ongoing efforts aim to establish SHTN1's functional relevance, leveraging this antibody as a critical reagent to bridge gaps in understanding its role in neural physiology and pathology.