关键信息
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基因名
SLC20A2
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简介
The SLC20A2 protein is a sodium-phosphate symporter that transports monovalent phosphate with a stoichiometry of two sodium ions per phosphate ion. Its role in bone mineralization is critical to bone quality and strength. SLC20A2 Protein, Human (sf9, His, MBP, FLAG) is the recombinant human-derived SLC20A2 protein, expressed by sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag.
- 应用
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别名
SLC20A2; Sodium-dependent phosphate transporter 2; Gibbon ape leukemia virus receptor 2; GLVR-2; Phosphate transporter 2; PiT-2; Pit2; hPit2; Solute carrier family 20 member 2
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种属
Human
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表达系统
Baculovirus
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标签
N-MBP;C-Flag;N-8*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q08357
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表达区间
A2-V652
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
SLC51B, also known as the small intestine-bile acid transporter (SIBAT), is part of the solute carrier family involved in the transport of bile acids across cell membranes. This protein is primarily expressed in the epithelial cells of the intestine and plays a crucial role in the enterohepatic circulation of bile acids, which are essential for lipid digestion and absorption. Recent studies have highlighted its significance in various physiological processes, including lipid metabolism, gut health, and the regulation of cholesterol levels. Dysregulation of SLC51B has been linked to several metabolic disorders, such as obesity, non-alcoholic fatty liver disease (NAFLD), and inflammatory bowel diseases. Research into SLC51B focuses on understanding its structural and functional properties, the mechanisms underlying its transport activity, and its potential as a therapeutic target for metabolic diseases. Innovative techniques, including molecular biology and biochemical assays, are employed to elucidate the pathways and regulatory networks involving SLC51B. Furthermore, studies on the effects of certain dietary components on SLC51B function may provide insights into nutritional strategies for managing metabolic health. As a result, SLC51B not only represents a critical player in bile acid homeostasis but also holds promise for the development of novel interventions aimed at improving metabolic health and preventing related diseases.
