| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| WB Predicted band size | 16 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human CST2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于CST2(Cystatin SA)抗体的3篇文献示例(注：内容为模拟概括，实际文献需通过学术数据库查询)：
1. **文献名称**：**"Cystatin SA as a Biomarker in Oral Squamous Cell Carcinoma"**
**作者**：Smith A, et al.
**摘要**：研究利用CST2抗体检测口腔鳞癌(OSCC)患者组织样本中的Cystatin SA表达，发现其高表达与肿瘤侵袭性相关，提示CST2可能作为诊断标志物。
2. **文献名称**：**"Immunohistochemical Analysis of CST2 in Salivary Gland Disorders"**
**作者**：Zhang L, et al.
**摘要**：通过CST2抗体进行免疫组化分析，发现Cystatin SA在慢性唾液腺炎患者中表达显著上调，可能参与局部炎症反应的调控。
3. **文献名称**：**"Development of a Monoclonal Antibody Against Human Cystatin SA and Its Diagnostic Applications"**
**作者**：Tanaka K, et al.
**摘要**：报道一种新型CST2单克隆抗体的开发，验证其在ELISA和Western blot中的特异性，并应用于唾液样本检测，为唾液腺功能障碍提供诊断工具。
如需具体文献，建议通过PubMed或Google Scholar以关键词“CST2 antibody”“Cystatin SA”检索近年研究。
**Background of CST2 Antibody**
The CST2 (Cystatin-SA2) antibody is a tool used to detect and study cystatin-SN (Cystatin S2), a member of the cystatin superfamily of cysteine protease inhibitors. Cystatins regulate proteolytic enzymes, such as cathepsins, which play roles in protein degradation, immune response, and cellular homeostasis. CST2 is primarily expressed in saliva, tears, and other bodily secretions, where it contributes to innate immunity by inhibiting microbial proteases and modulating inflammation.
Research on CST2 has expanded due to its potential involvement in diseases, including cancers, inflammatory disorders, and oral pathologies. For example, elevated CST2 levels are observed in certain cancers, suggesting a role in tumor progression or immune evasion. The CST2 antibody enables researchers to analyze its expression patterns, quantify protein levels in biological samples (e.g., via Western blot, ELISA, or immunohistochemistry), and explore its functional mechanisms.
Recent studies also highlight CST2’s diagnostic potential as a biomarker for conditions like Sjögren’s syndrome or head and neck cancers. However, its precise biological roles remain under investigation, necessitating reliable antibodies for experimental validation. Commercial CST2 antibodies are typically raised against specific epitopes, with validation in relevant tissues or cell lines to ensure specificity. Ongoing research aims to clarify CST2’s dual roles in protection and pathology, driving demand for high-quality reagents to support both basic and clinical studies.
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