| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | GHL; GHV; GH-V; hGH-V |
| WB Predicted band size | 25 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human GH2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于GH2抗体的3篇参考文献摘要，按研究方向和内容分类整理：
1. **文献名称**：*Production and Characterization of a Monoclonal Antibody Specific for Chicken Growth Hormone (GH2)*
**作者**：Smith A, et al.
**摘要**：研究团队开发了一种针对鸡生长激素GH2的单克隆抗体，验证了其在ELISA和Western blot中的高特异性，成功应用于检测禽类血清和组织样本中的GH2表达水平。
2. **文献名称**：*GH2 Antibody-Mediated Regulation of Somatic Growth in Zebrafish*
**作者**：Chen L, Wang Y.
**摘要**：通过免疫中和实验发现，GH2抗体可特异性阻断斑马鱼生长激素信号通路，导致体长发育迟缓，揭示了GH2在脊椎动物生长调控中的关键作用。
3. **文献名称**：*Cross-Reactivity Analysis of Anti-GH2 Antibodies in Mammalian Models*
**作者**：Rodriguez J, et al.
**摘要**：系统性评估了多种GH2抗体在小鼠和大鼠中的交叉反应性，发现部分抗体因物种特异性差异导致检测灵敏度降低，为跨物种GH2研究提供了抗体选择依据。
注：以上文献信息为示例性质，实际引用时建议通过PubMed或Web of Science等数据库核实最新研究。若需具体文献来源或扩展领域(如人类GH2研究)，可进一步补充说明。
GH2 antibody targets growth hormone 2 (GH2), a peptide hormone primarily involved in growth regulation, metabolism, and cell repair. GH2. encoded by the *GH2* gene, is structurally similar to growth hormone 1 (GH1) but differs in expression patterns and evolutionary conservation. While GH1 is the dominant form in humans, GH2 is more prominent in certain species, such as fish, and may play roles in developmental or species-specific physiological processes.
In research, GH2 antibodies are critical tools for detecting and quantifying GH2 in biological samples via techniques like ELISA, Western blotting, or immunohistochemistry. These antibodies help elucidate GH2's functional roles, including its interaction with growth hormone receptors (GHR) and involvement in signaling pathways like JAK-STAT. Dysregulation of GH2-related pathways has been linked to growth disorders, metabolic syndromes, and some cancers, making such antibodies valuable for both basic and clinical studies.
Most GH2 antibodies are monoclonal or polyclonal, raised in hosts like rabbits or mice, with specificity validated through epitope mapping. Cross-reactivity with GH1 or other pituitary hormones is a key consideration during experimental design. Ongoing research focuses on refining antibody specificity and exploring therapeutic applications, such as targeting GH2 in hormone-responsive diseases.
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