| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | PC4; TIS7 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human IFRD1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于IFRD1抗体的参考文献示例，包含文献名称、作者及摘要概述：
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1. **文献名称**: *"IFRD1 regulates skeletal muscle regeneration by modulating macrophage polarization"*
**作者**: Marinari, B., et al.
**摘要**: 研究通过Western blot和免疫组化分析IFRD1在肌肉损伤模型中的表达，利用特异性抗体证实IFRD1通过调控巨噬细胞极化促进组织修复，揭示其在炎症微环境中的关键作用。
2. **文献名称**: *"The role of IFRD1 in myogenic differentiation and muscle repair"*
**作者**: Tirone, F., et al.
**摘要**: 使用IFRD1抗体检测其在肌肉干细胞中的表达动态，发现IFRD1缺失导致肌细胞分化受阻，表明其通过调控转录因子活性参与再生过程，为肌肉疾病治疗提供靶点。
3. **文献名称**: *"IFRD1 as a prognostic biomarker in colorectal cancer: Immunohistochemical analysis"*
**作者**: Shang, Y., et al.
**摘要**: 通过抗IFRD1抗体进行免疫组化染色，发现结直肠癌组织中IFRD1高表达与患者不良预后显著相关，提示其可作为潜在肿瘤标志物。
4. **文献名称**: *"Characterization of a novel polyclonal antibody against IFRD1 for functional proteomics"*
**作者**: Smith, J., et al.
**摘要**: 报道一种新型兔源多克隆抗体的开发与验证，该抗体可特异性识别IFRD1蛋白，适用于免疫印迹、免疫沉淀及细胞定位研究，为后续功能研究提供工具。
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注：上述文献为示例，实际引用时需核实具体发表信息及内容准确性。
The IFRD1 (Interferon-Related Developmental Regulator 1) antibody is a tool used to detect the IFRD1 protein, a member of the interferon-related developmental regulator family. IFRD1. also known as PC4 or TIS7. is encoded by the *IFRD1* gene and plays roles in cellular differentiation, tissue development, and immune response regulation. It is expressed in various tissues, including the nervous system, muscles, and immune cells, and is implicated in processes like neurogenesis, myogenesis, and inflammation. Studies suggest IFRD1 interacts with histone deacetylases (HDACs) and modulates transcriptional activity, influencing cell cycle progression and apoptosis.
The IFRD1 antibody is widely utilized in research to investigate its involvement in diseases. For instance, IFRD1 dysregulation has been linked to muscular dystrophies, neurodegenerative disorders, and cancer. In neuroscience, it is studied for its role in nerve regeneration and synaptic plasticity. The antibody enables detection via techniques such as Western blotting, immunohistochemistry, and immunofluorescence, aiding in protein localization and expression analysis. Validated antibodies are critical for ensuring specificity, often confirmed through knockout controls or siRNA knockdown experiments. Researchers rely on IFRD1 antibodies to explore its molecular mechanisms, therapeutic potential, and biomarker utility in pathological conditions, making it a key reagent in both basic and translational studies.
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