| WB | 1/200-1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/1000-1/2000 | Human,Mouse,Rat |
| Aliases | LNP; ANKT; SAPL; BM037; NUSAP; Q0310; PRO0310p1 |
| WB Predicted band size | 49 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human NUSAP1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于NUSAP1抗体的3篇参考文献示例(注：文献为模拟示例，实际引用需核实)：
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1. **文献名称**：*NUSAP1 promotes hepatocellular carcinoma progression by recruiting polycomb repressive complex 1 through histone methylation modification*
**作者**：Li X, Zhang Y, Zheng Y
**摘要内容**：研究利用NUSAP1抗体进行免疫组化分析，发现NUSAP1在肝癌组织中高表达，并通过调控组蛋白甲基化促进肿瘤侵袭，提示其作为潜在治疗靶点。
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2. **文献名称**：*NUSAP1 interacts with microtubules and predicts poor prognosis in triple-negative breast cancer*
**作者**：Wang C, Liu H, Patel RR
**摘要内容**：通过Western blot和免疫荧光技术(使用特异性NUSAP1抗体)，证实NUSAP1与微管蛋白相互作用，其过表达与三阴性乳腺癌患者生存率降低显著相关。
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3. **文献名称**：*A novel NUSAP1 antibody-based assay for early detection of pancreatic ductal adenocarcinoma*
**作者**：Kim S, Gupta R, Park J
**摘要内容**：开发了一种基于NUSAP1抗体的ELISA检测方法，验证其在胰腺导管腺癌患者血清中的高灵敏度和特异性，为早期诊断提供新工具。
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如需进一步文献检索，建议通过PubMed或Google Scholar以“NUSAP1 antibody”或“NUSAP1 immunohistochemistry”为关键词筛选近年研究。
The NUSAP1 (Nucleolar and Spindle Associated Protein 1) antibody is a tool used to detect and study the NUSAP1 protein, a critical regulator of mitotic progression and chromosomal stability. NUSAP1 is a microtubule-associated protein enriched during the G2/M phase of the cell cycle, playing roles in spindle assembly, chromosome segregation, and cytokinesis. It contains distinct domains for microtubule binding, chromatin interaction, and protein recruitment, enabling its involvement in maintaining genomic integrity. Dysregulation of NUSAP1 has been linked to cancer progression, with overexpression observed in malignancies like breast, prostate, and colorectal cancers, where it correlates with poor prognosis, metastasis, and therapy resistance.
The NUSAP1 antibody is widely utilized in techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to assess protein expression levels, subcellular localization, and functional interactions in both research and clinical contexts. Studies employing this antibody have highlighted NUSAP1's potential as a biomarker for cancer diagnosis and as a therapeutic target, given its role in promoting cell proliferation and survival. Additionally, NUSAP1 inhibition has been shown to induce mitotic defects and apoptosis in cancer cells, underscoring its relevance in oncology research. The antibody's specificity and reliability make it essential for elucidating NUSAP1's mechanisms in cell cycle regulation and cancer biology.
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