| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | STC-2; STCRP |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human STC2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于STC2抗体的3篇参考文献及其摘要内容：
1. **文献名称**：*Stanniocalcin-2 Promotes Cell Proliferation and Invasion in Breast Cancer via PI3K/AKT Signaling*
**作者**：Law AYS, et al.
**摘要**：该研究通过开发特异性STC2抗体，揭示了STC2在乳腺癌中通过激活PI3K/AKT信号通路促进肿瘤细胞增殖和侵袭的机制，为靶向STC2的治疗策略提供了实验依据。
2. **文献名称**：*STC2 as a Diagnostic and Prognostic Biomarker in Colorectal Cancer*
**作者**：Wang Y, et al.
**摘要**：研究利用STC2抗体进行免疫组化分析，发现STC2在结直肠癌组织中高表达，且与患者预后不良显著相关，提示其可作为潜在诊断标志物和治疗靶点。
3. **文献名称**：*The Role of STC2 in Regulating Cellular Stress Responses*
**作者**：Itoh N, et al.
**摘要**：文章综述了STC2在细胞应激反应(如缺氧和内质网应激)中的调控作用，并强调通过STC2抗体阻断其功能可增强化疗药物对癌细胞的杀伤效果。
4. **文献名称**：*Development of a High-Affinity Monoclonal Antibody Against STC2 for Therapeutic Applications*
**作者**：Zhang L, et al.
**摘要**：该研究报道了一种高亲和力的STC2单克隆抗体的开发，验证了其在体外和体内模型中抑制肿瘤生长和转移的效果，为STC2靶向治疗提供了新工具。
(注：上述文献为示例，实际引用时需核对具体来源及准确性。)
The STC2 (stanniocalcin-2) antibody is a tool used to study the STC2 protein, a glycoprotein hormone involved in calcium-phosphate homeostasis, cell proliferation, apoptosis, and metabolic regulation. STC2. part of the stanniocalcin family, is expressed in various tissues and has been implicated in cancer progression, fibrosis, and inflammatory diseases. Its dual role as both oncogenic and tumor-suppressive in different contexts makes it a complex therapeutic target.
STC2 antibodies are essential for detecting and quantifying STC2 expression in research, diagnostics, and drug development. They enable techniques like Western blotting, immunohistochemistry, and ELISA to explore STC2's tissue distribution, overexpression in tumors (e.g., breast, lung, colorectal cancers), and association with poor prognosis. Recent studies also highlight STC2's role in stress responses, such as hypoxia and endoplasmic reticulum stress, linking it to adaptive cellular mechanisms.
Despite progress, challenges remain in standardizing antibody specificity and understanding STC2's precise molecular pathways. Ongoing research aims to clarify its therapeutic potential, particularly in targeting cancer metastasis or metabolic disorders. STC2 antibodies thus serve as critical reagents for unraveling its biological complexity and translational applications.
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