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Rabbit Polyclonal ZFP2 Antibody

  • 中文名: ZFP2抗体
  • 别    名: ZNF751
货号: IPDX09019
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/30-1/150 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/2000-1/10000 Human,Mouse,Rat

产品详情

AliasesZNF751
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human ZFP2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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参考文献

以下是关于ZFP2抗体的模拟参考文献示例(注:内容为假设性示例,实际文献需通过学术数据库验证):

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1. **文献名称**: "ZFP2 regulates pluripotency in embryonic stem cells through interaction with OCT4"

**作者**: Smith A, et al.

**摘要**: 本研究利用ZFP2特异性抗体进行免疫共沉淀实验,发现ZFP2蛋白与多能性因子OCT4存在直接相互作用,揭示了其在胚胎干细胞自我更新中的调控机制。

2. **文献名称**: "ZFP2 expression profiling in prostate cancer tissues using immunohistochemistry"

**作者**: Johnson R, et al.

**摘要**: 通过ZFP2抗体进行免疫组化分析,发现ZFP2在前列腺癌组织中显著高表达,且与患者不良预后相关,提示其作为潜在肿瘤标志物的可能性。

3. **文献名称**: "ZFP2 antibody-based ChIP-seq identifies target genes in epigenetic regulation"

**作者**: Brown K, et al.

**摘要**: 采用ZFP2抗体进行染色质免疫沉淀测序(ChIP-seq),鉴定了ZFP2结合的基因组区域,表明其通过调控组蛋白修饰参与神经发育相关基因的表观遗传沉默。

4. **文献名称**: "ZFP2 modulates hepatic regeneration via Wnt/β-catenin signaling"

**作者**: Zhang Y, et al.

**摘要**: 利用ZFP2抗体进行Western blot和免疫荧光实验,证实ZFP2在肝脏再生过程中动态表达,并通过激活Wnt通路促进肝细胞增殖。

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建议通过PubMed、Google Scholar等平台检索真实文献(关键词:ZFP2 antibody, ZFP2 zinc finger protein),并优先选择近五年内发表的论文以获取最新进展。

背景信息

The ZFP2 antibody is designed to target ZFP2. a member of the zinc finger protein (ZFP) family, which plays roles in transcriptional regulation and chromatin remodeling. Zinc finger proteins typically contain conserved zinc-binding domains that facilitate DNA, RNA, or protein interactions. ZFP2. also known as ZNF2 or ZNF538 in some contexts, is implicated in developmental processes and cellular differentiation. While its exact biological functions remain under investigation, ZFP2 is hypothesized to regulate gene expression through epigenetic modifications or direct DNA binding, potentially influencing stem cell pluripotency or tissue-specific gene programs.

Antibodies against ZFP2 are valuable tools for studying its expression patterns, subcellular localization, and interactions in various biological contexts. They are commonly used in techniques like Western blotting, immunofluorescence, and chromatin immunoprecipitation (ChIP) to elucidate ZFP2's role in health and disease. Research has explored its involvement in cancer, neurodevelopment, and reproductive biology, though mechanistic insights are still emerging. Commercial ZFP2 antibodies are often raised in rabbits or mice using recombinant protein fragments or synthetic peptides, with validation steps confirming specificity. As interest in zinc finger proteins grows due to their therapeutic potential, ZFP2 antibodies contribute to decoding its functional relevance in gene regulatory networks and disease pathways.

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