| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | S15a; DBA20 |
| WB Predicted band size | 15 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human RPS15A |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇关于RPS15A抗体的代表性文献示例(注：文献名称和作者为虚构模拟，供参考格式)：
1. **文献名称**: "RPS15A promotes colorectal cancer progression via mTOR signaling pathway"
**作者**: Li et al.
**摘要**: 研究发现RPS15A在结直肠癌组织中高表达，通过激活mTOR通路增强肿瘤细胞增殖和转移能力，抗体用于检测其蛋白表达水平与临床预后的相关性。
2. **文献名称**: "Antibody-based profiling of RPS15A reveals its role in ribosome biogenesis and MYC-driven oncogenesis"
**作者**: Garcia-Rivera et al.
**摘要**: 利用特异性抗体揭示RPS15A在核糖体生物合成中的功能，并发现其与MYC原癌基因协同调控乳腺癌细胞周期进程和凋亡抵抗。
3. **文献名称**: "RPS15A as a novel biomarker for hepatocellular carcinoma: Validation by immunohistochemistry"
**作者**: Wang & Nakamura
**摘要**: 通过免疫组化抗体验证RPS15A在肝癌组织中的高表达，其表达水平与患者生存率显著相关，提示其作为潜在诊断标志物的价值。
4. **文献名称**: "RPS15A interacts with viral proteins during influenza infection: A proteomic study"
**作者**: Chen et al.
**摘要**: 使用RPS15A抗体进行免疫共沉淀实验，发现其与流感病毒NS1蛋白相互作用，可能参与病毒复制和宿主细胞应激反应调控。
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**注**：实际文献需通过PubMed/Google Scholar以关键词"RPS15A antibody"或"RPS15A function"检索。以上案例展示了该抗体在癌症机制、病毒互作等领域的研究方向。
The RPS15A antibody is a research tool designed to detect and study Ribosomal Protein S15a (RPS15A), a component of the 40S ribosomal subunit involved in mRNA translation. RPS15A plays a critical role in ribosome biogenesis and protein synthesis, but emerging studies suggest its involvement in non-ribosomal functions, including cell cycle regulation, apoptosis, and DNA damage response. Dysregulation of RPS15A has been linked to cancers, neurodegenerative disorders, and viral infections, making it a biomarker of interest.
RPS15A antibodies are typically produced in host species like rabbits or mice using immunogenic peptides or recombinant proteins. They are widely used in techniques such as Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and co-immunoprecipitation (Co-IP) to investigate RPS15A expression, localization, and interactions in cellular or tissue samples. Validated antibodies help researchers explore RPS15A's role in diseases, particularly its overexpression in tumors (e.g., colorectal, breast cancers) and association with poor prognosis. Recent studies also highlight its potential crosstalk with oncogenic signaling pathways like PI3K/AKT and MAPK. As ribosomopathies and translation-targeted therapies gain attention, RPS15A antibodies remain essential for dissecting ribosome-related mechanisms in health and disease.
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