| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | HHGP |
| WB Predicted band size | 26 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Full length fusion protein |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇关于PRTFDC1抗体的示例参考文献(注：文献为假设性示例，实际引用需核实)：
1. **文献名称**: "PRTFDC1 modulates purine metabolism and promotes tumor progression in pancreatic cancer"
**作者**: Zhang Y, et al.
**摘要**: 本研究利用PRTFDC1特异性抗体，通过免疫组化和Western blot分析发现，PRTFDC1在胰腺癌中高表达，并通过调节嘌呤代谢途径促进肿瘤细胞增殖和侵袭。
2. **文献名称**: "A monoclonal antibody against PRTFDC1 reveals its expression pattern in normal and cancerous tissues"
**作者**: Tanaka K, et al.
**摘要**: 作者开发了一种高特异性PRTFDC1单克隆抗体，验证了其在多种正常组织及肿瘤中的表达差异，并证实PRTFDC1在卵巢癌中显著下调，可能与预后相关。
3. **文献名称**: "PRTFDC1 interacts with mitochondrial proteins and regulates apoptosis in neuronal cells"
**作者**: Müller S, et al.
**摘要**: 通过免疫共沉淀(Co-IP)和免疫荧光技术结合PRTFDC1抗体，研究发现PRTFDC1与线粒体蛋白Bcl-2家族成员相互作用，影响神经元细胞的凋亡通路。
4. **文献名称**: "Loss of PRTFDC1 enhances chemoresistance in colorectal cancer via dysregulated nucleotide synthesis"
**作者**: Wang L, et al.
**摘要**: 使用PRTFDC1抗体进行功能研究，发现PRTFDC1缺失通过干扰核苷酸合成通路导致结直肠癌细胞对5-FU化疗耐药，提示其作为治疗靶点的潜力。
建议通过PubMed或Google Scholar以“PRTFDC1 antibody”为关键词检索最新文献获取真实数据。
The PRTFDC1 (phosphoribosyl transferase domain-containing protein 1) antibody is a tool used to detect and study the PRTFDC1 protein, a less characterized member of the phosphoribosyltransferase (PRTase) family. PRTFDC1 shares structural homology with enzymes involved in nucleotide metabolism, particularly purine biosynthesis, though its exact biochemical function remains unclear. Research suggests its potential role in cellular processes such as proliferation, differentiation, and tumorigenesis. Aberrant expression of PRTFDC1 has been linked to several cancers, including oral squamous cell carcinoma and ovarian cancer, where it may act as an oncogene or tumor suppressor depending on context.
The PRTFDC1 antibody enables researchers to investigate the protein's expression patterns, subcellular localization, and interactions in normal and diseased tissues. It is commonly used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Studies utilizing this antibody have revealed tissue-specific expression profiles, with higher levels observed in brain, muscle, and certain epithelial tissues. Recent work also explores its association with chemotherapy resistance and metabolic reprogramming in tumors. Despite progress, the mechanistic pathways involving PRTFDC1 require further elucidation, highlighting the continued importance of this antibody in basic and translational research.
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