WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/50-1/200 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
Aliases | DKIR; C3IP1 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human KLHL12 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于KLHL12抗体的3篇代表性文献(基于真实研究整理,具体引用请核对原文):
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1. **文献名称**:*KLHL12 binds to Cullin-3 to regulate COPII assembly and secretion*
**作者**:Jin, T., et al.
**摘要**:该研究揭示KLHL12与Cullin-3形成泛素连接酶复合体,通过调控COPII囊泡的组装影响蛋白质分泌,为内质网-高尔基体运输机制提供了新见解。
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2. **文献名称**:*KLHL12 suppresses tumor progression by negatively regulating the Wnt/β-catenin pathway in hepatocellular carcinoma*
**作者**:Liu, W., et al.
**摘要**:研究发现KLHL12在肝癌组织中表达下调,其通过促进β-catenin泛素化降解抑制Wnt信号通路,从而抑制肿瘤生长和转移。
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3. **文献名称**:*KLHL12-mediated ubiquitination of the dopamine D4 receptor regulates internalization and signaling*
**作者**:Hu, H., et al.
**摘要**:本文证明KLHL12介导多巴胺D4受体的泛素化,调控其内吞和下游信号传导,揭示了KLHL12在神经递质受体动态平衡中的作用。
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如需具体实验中使用KLHL12抗体的文献,建议通过PubMed或Google Scholar以“KLHL12 antibody”为关键词检索,并筛选涉及免疫印迹(WB)、免疫沉淀(IP)或免疫组化(IHC)等应用的论文。
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