Rabbit Polyclonal C3orf38 Antibody

The C3orf38 antibody targets the protein encoded by the C3orf38 gene (Chromosome 3 Open Reading Frame 38), a poorly characterized gene located on human chromosome 3 (3p21.31). This gene is conserved across vertebrates, suggesting potential biological significance, though its precise molecular functions remain unclear. Limited studies indicate that C3orf38 may play roles in cellular processes such as cell proliferation, apoptosis, or DNA repair, with possible implications in cancer. For instance, altered C3orf38 expression has been observed in certain tumors, though its oncogenic or tumor-suppressive role requires further validation. The C3orf38 antibody is primarily used as a research tool to detect and study the expression, localization, and interactions of the C3orf38 protein in various tissues or cell lines via techniques like Western blotting, immunohistochemistry, or immunofluorescence. Commercial antibodies are typically developed using immunogens derived from specific epitopes of the predicted protein structure. However, due to the gene’s understudied nature, antibody validation often relies on overexpression or knockdown models to confirm specificity. Researchers studying chromosome 3-associated disorders, rare genetic conditions, or cancer mechanisms may utilize this antibody to explore C3orf38’s functional relevance. Current challenges include the lack of comprehensive functional data and standardized protocols, highlighting the need for further investigation into its biological pathways and disease associations.