Rabbit Polyclonal CPNE3 Antibody

The CPNE3 antibody is a tool used to detect Copine III (CPNE3), a member of the copine protein family characterized by calcium-dependent phospholipid-binding domains. CPNE3 is involved in membrane trafficking, signal transduction, and cellular processes such as proliferation, differentiation, and apoptosis. It is ubiquitously expressed, with notable roles in the nervous system, immune response, and cancer progression. Studies suggest CPNE3 interacts with membrane phospholipids and proteins to regulate intracellular signaling pathways, including EGFR and Wnt/β-catenin, influencing tumor growth and metastasis. Overexpression of CPNE3 has been linked to poor prognosis in cancers like hepatocellular carcinoma and glioblastoma, highlighting its potential as a therapeutic target or biomarker. The CPNE3 antibody enables researchers to study its expression patterns, subcellular localization, and functional mechanisms through techniques like Western blotting, immunohistochemistry, and immunofluorescence. Validated for specificity and sensitivity, this antibody is critical for elucidating CPNE3's role in disease pathogenesis and normal physiology, aiding both basic research and clinical investigations.