| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| WB Predicted band size | 38 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human C11orf49 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇关于C11orf49抗体的虚构参考文献(基于学术文献常见结构模拟，实际文献需根据真实数据库查询)：
1. **文献名称**: "Characterization of C11orf49 antibody for detecting protein expression in lung adenocarcinoma"
**作者**: Li, X., et al.
**摘要**: 本研究开发了一种高特异性C11orf49多克隆抗体，通过免疫印迹和免疫组化验证其在肺癌组织中的表达上调，发现C11orf49高表达与患者预后不良相关。
2. **文献名称**: "C11orf49 interacts with TP53: A functional study using co-immunoprecipitation with specific antibodies"
**作者**: Wang, Y., et al.
**摘要**: 利用C11orf49抗体进行免疫共沉淀实验，首次证明C11orf49蛋白与TP53存在物理相互作用，并通过敲低实验揭示其在DNA损伤修复通路中的潜在作用。
3. **文献名称**: "Structural insights into C11orf49 via epitope mapping of monoclonal antibodies"
**作者**: Tanaka, K., et al.
**摘要**: 通过制备针对C11orf49不同结构域的单克隆抗体，结合X射线晶体学解析其抗原表位，为研究该蛋白的三维结构及功能域提供了工具。
注：以上内容为模拟生成，实际文献需通过PubMed、Web of Science等平台以"C11orf49 AND antibody"为关键词检索。若需真实文献，建议补充具体研究背景(如疾病方向或实验类型)。
The C11orf49 antibody is a research tool designed to target the protein encoded by the *C11orf49* gene (Chromosome 11 Open Reading Frame 49), a poorly characterized gene located on human chromosome 11. While the exact biological function of C11orf49 remains unclear, emerging studies suggest its potential involvement in cellular processes such as cell cycle regulation, DNA repair, or protein-protein interactions. The gene has been implicated in various contexts, including cancer, where altered expression levels correlate with tumor progression or patient outcomes in certain malignancies, such as breast or colorectal cancer.
C11orf49 antibodies are typically developed as polyclonal or monoclonal reagents for applications like Western blotting, immunohistochemistry, or immunofluorescence to detect protein expression, localization, and interactions. Their use helps researchers explore the gene’s role in disease mechanisms or normal physiology. However, the lack of comprehensive functional studies and standardized validation protocols poses challenges, leading to variability in antibody performance across studies.
Interest in C11orf49 has grown alongside advances in proteomics and genomic screening, which highlight its potential as a biomarker or therapeutic target. Current research focuses on elucidating its molecular interactions and pathways, often leveraging antibodies to validate findings in model systems. Despite limited data, the C11orf49 antibody remains a critical reagent for probing this understudied protein’s contributions to health and disease.
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