| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | PAP; PDCD9; S30mt; MRP-S30 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human MRPS30 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
+ +
以下是关于MRPS30抗体的3篇参考文献(文献信息为虚构模拟，仅供示例参考)：
1. **文献名称**：MRPS30 regulates apoptosis via mitochondrial translation pathway
**作者**：Chen L, et al.
**摘要**：本研究通过Western blot和免疫共沉淀实验，利用特异性MRPS30抗体证明MRPS30通过调控线粒体翻译活性参与细胞凋亡，其表达下调导致凋亡信号通路激活。
2. **文献名称**：MRPS30 antibody-based detection in breast cancer progression
**作者**：Wang Y, et al.
**摘要**：开发了一种高灵敏度的MRPS30单克隆抗体，用于分析乳腺癌组织中MRPS30的蛋白表达水平，发现其低表达与肿瘤转移和不良预后显著相关。
3. **文献名称**：Mitochondrial ribosomal protein S30 interacts with Bcl-2 family proteins
**作者**：Kim S, et al.
**摘要**：通过免疫荧光和流式细胞术结合MRPS30抗体，揭示MRPS30与Bcl-2家族蛋白的相互作用，提出其在调控线粒体膜电位及程序性细胞死亡中的新机制。
*注：以上文献及摘要内容为模拟生成，实际研究中请通过PubMed或专业数据库检索具体文献。*
The MRPS30 antibody is a research tool targeting the Mitochondrial Ribosomal Protein S30. a component of the 28S subunit within the mitochondrial ribosome. Mitochondrial ribosomes are specialized for synthesizing proteins essential for oxidative phosphorylation (OXPHOS), a critical energy-producing pathway. MRPS30. encoded by the nuclear genome, is imported into mitochondria and plays a structural or functional role in ribosomal assembly or translation. Antibodies against MRPS30 enable the study of mitochondrial protein synthesis dynamics, ribosome biogenesis, and their dysregulation in diseases.
These antibodies are widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to detect MRPS30 expression levels, subcellular localization, and interactions. Research applications include investigating mitochondrial dysfunction in neurodegenerative disorders (e.g., Parkinson's disease), metabolic syndromes, and cancers, where altered mitochondrial translation may contribute to pathogenesis. Studies suggest MRPS30's potential role in apoptosis regulation and cancer cell survival, making it a biomarker candidate in oncology. Additionally, MRPS30 antibodies aid in exploring inherited mitochondrial disorders linked to mutations in ribosomal proteins. Their specificity and reliability are validated using mitochondrial extracts or knockout controls to ensure accurate detection. Overall, MRPS30 antibodies are vital for elucidating mitochondrial biology and its implications in health and disease.
×
