| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | S10; DBA9 |
| WB Predicted band size | 19 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human RPS10 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于RPS10抗体的模拟参考文献示例(仅供参考，具体文献需通过学术数据库核实)：
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1. **文献名称**: *RPS10 overexpression correlates with poor prognosis in colorectal cancer via mTOR signaling activation*
**作者**: Smith A, et al.
**摘要**: 本研究利用RPS10特异性抗体进行免疫组化分析，发现结直肠癌组织中RPS10蛋白表达显著升高，且与mTOR通路激活及患者生存率降低相关，提示其作为潜在预后标志物的价值。
2. **文献名称**: *Ribosomal protein S10 regulates ribosome biogenesis through interaction with 18S rRNA*
**作者**: Zhang Y, et al.
**摘要**: 通过Western Blot和免疫共沉淀技术(使用RPS10抗体)，揭示了RPS10在核糖体RNA加工中的关键作用，并发现其缺失会导致核糖体组装异常，影响细胞增殖。
3. **文献名称**: *Developmental role of RPS10 in zebrafish neural crest migration*
**作者**: Johnson R, et al.
**摘要**: 利用RPS10抗体的免疫荧光定位，证明RPS10在斑马鱼胚胎神经嵴细胞迁移中不可或缺，敲除后引发颅面发育缺陷，提示其与先天性疾病的潜在关联。
4. **文献名称**: *Autoantibody against RPS10 in systemic lupus erythematosus: Diagnostic implications*
**作者**: Lee H, et al.
**摘要**: 通过ELISA和蛋白质印迹法(基于RPS10抗体)，发现系统性红斑狼疮患者血清中抗RPS10自身抗体水平升高，或可作为疾病诊断的新型生物标志物。
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**备注**：以上文献为示例性概括，实际研究中请通过PubMed、Google Scholar等平台以“RPS10 antibody”、“anti-RPS10”等关键词检索，并筛选应用方向(如疾病机制、分子互作、诊断标志物等)。若需具体文献，建议提供研究背景以进一步精准推荐。
The ribosomal protein S10 (RPS10) is a component of the 40S subunit of eukaryotic ribosomes, playing a critical role in mRNA translation and ribosome biogenesis. As part of the conserved ribosomal machinery, RPS10 contributes to ribosome assembly and protein synthesis fidelity. Beyond its canonical role, RPS10 has been implicated in extraribosomal functions, including interactions with cellular pathways regulating apoptosis, cell proliferation, and stress responses. Dysregulation of RPS10 expression or mutations in its coding gene have been associated with developmental disorders, such as Diamond-Blackfan anemia, and cancers, including colorectal and hepatocellular carcinomas, suggesting its potential as a biomarker or therapeutic target.
RPS10 antibodies are immunological tools designed to detect and quantify RPS10 in experimental settings. These antibodies are widely used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to study RPS10 expression patterns, subcellular localization, and interactions in normal and pathological tissues. Their applications extend to investigating ribosomopathies, cancer biology, and cellular stress mechanisms. Validation of RPS10 antibodies involves specificity testing against recombinant proteins or gene-edited cell lines to ensure minimal cross-reactivity with other ribosomal proteins. Commercially available antibodies are typically raised in rabbits or mice, with clonal variants offering enhanced reproducibility. Ongoing research continues to explore RPS10's dual roles in ribosomal function and disease, underscoring the importance of reliable antibodies in mechanistic and translational studies.
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