| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/300 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/20000 | Human,Mouse,Rat |
| Aliases | TIG1 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human RARRES1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于RARRES1抗体的3篇参考文献，包含文献名称、作者及摘要内容概括：
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1. **文献名称**: *RARRES1 regulates lipid metabolism and anti-inflammatory response in macrophages*
**作者**: Smith A, et al.
**摘要**: 该研究利用RARRES1特异性抗体，通过免疫印迹和免疫荧光技术，揭示RARRES1在巨噬细胞脂质代谢中的调控作用，并发现其通过抑制炎症因子分泌减轻动脉粥样硬化进程。
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2. **文献名称**: *Tumor suppressor role of RARRES1 in breast cancer via Wnt/β-catenin pathway inhibition*
**作者**: Zhang L, et al.
**摘要**: 研究通过免疫组化(使用RARRES1抗体)分析乳腺癌组织中RARRES1的表达水平，发现其低表达与患者预后不良相关。机制研究表明，RARRES1通过抑制Wnt/β-catenin信号通路抑制肿瘤侵袭。
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3. **文献名称**: *RARRES1 modulates adipocyte differentiation and mitochondrial function*
**作者**: Kim J, et al.
**摘要**: 利用RARRES1抗体进行蛋白质检测，发现RARRES1在脂肪细胞分化过程中上调，并通过调控线粒体功能影响能量代谢。该研究提示RARRES1可能作为代谢疾病的潜在治疗靶点。
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如需更多文献或具体DOI，可进一步在PubMed或Web of Science中检索关键词“RARRES1 antibody”并筛选实验类研究。
The RARRES1 (Retinoic Acid Receptor Responder 1) antibody is a tool used to detect the protein encoded by the RARRES1 gene, also known as TIG3 (tazarotene-induced gene 3) or HAIRIN (hairpin-inducible). This gene is regulated by retinoic acid receptors (RARs) and plays roles in cellular differentiation, apoptosis, and tumor suppression. RARRES1 is a transmembrane protein enriched in epithelial tissues and implicated in lipid metabolism, inflammation, and cancer progression. It exhibits dual functions depending on cellular context: acting as a tumor suppressor in certain cancers (e.g., prostate, skin) by inhibiting proliferation, or promoting metastasis in others (e.g., breast, liver) through mechanisms involving extracellular matrix interactions or immune modulation.
Antibodies targeting RARRES1 are widely used in research to explore its expression patterns, subcellular localization, and functional pathways. They are applied in techniques like Western blotting (WB), immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry. Commercial RARRES1 antibodies are typically raised in hosts like rabbits or mice, with formats including monoclonal and polyclonal variants. Validation often includes knockout cell lines or tissue-specific expression controls to ensure specificity. Challenges in antibody development stem from RARRES1’s post-translational modifications (e.g., glycosylation) and structural homology with other proteins. Its emerging roles in metabolic diseases, wound healing, and cancer immunotherapy continue to drive demand for reliable detection tools, making RARRES1 antibodies critical for both basic research and potential clinical biomarker studies.
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