Rabbit Polyclonal GH1 Antibody

GH1 antibody targets growth hormone 1 (GH1), a peptide hormone critical for growth, metabolism, and cell repair. Produced by somatotroph cells in the anterior pituitary, GH1 regulates postnatal development via the GH-IGF-1 axis. As a key biomarker in endocrine research, GH1 is implicated in disorders like growth hormone deficiency, gigantism, and acromegaly. Antibodies against GH1 are typically monoclonal or polyclonal, generated in hosts like mice, rabbits, or goats, and validated for applications such as Western blotting, immunohistochemistry (IHC), and ELISA. These tools enable precise detection of GH1 expression in tissues or serum, aiding in the study of pituitary function, tumor characterization, and metabolic diseases. Commercially available GH1 antibodies often feature specificity for conserved epitopes across species, facilitating cross-disciplinary research. Their clinical utility includes diagnosing pituitary adenomas and monitoring recombinant GH therapy. However, variability in antibody performance (e.g., cross-reactivity with placental GH variants) necessitates rigorous validation. Recent studies also explore GH1's role in aging, cancer proliferation, and immune modulation, expanding the antibody's relevance in translational research. Proper storage (often at -20°C with carrier proteins) and optimized dilution protocols are essential for maintaining assay reproducibility.