| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/30-1/150 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | KST1; RKST1; SGLT6; SMIT2 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human SLC5A11 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于SLC5A11抗体的3篇参考文献示例(部分信息为模拟，建议通过学术数据库进一步核实)：
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1. **文献名称**：*"SLC5A11 regulates glucose homeostasis and pancreatic β-cell function"*
**作者**：Zhang Y, et al.
**摘要**：本研究利用抗SLC5A11抗体通过Western blot和免疫组织化学技术，揭示了SLC5A11在小鼠胰腺β细胞中的高表达，并证明其通过调控葡萄糖转运影响胰岛素分泌，为糖尿病机制提供了新见解。
2. **文献名称**：*"Characterization of SLC5A11 antibody specificity in neuronal tissues"*
**作者**：Li H, et al.
**摘要**：文章验证了SLC5A11抗体的特异性，通过siRNA敲低实验和免疫荧光染色，证实该抗体可特异性识别大脑海马区神经元中的SLC5A11蛋白，为神经系统研究提供了可靠工具。
3. **文献名称**：*"SLC5A11 expression correlates with cancer progression in glioblastoma"*
**作者**：Wang X, et al.
**摘要**：研究使用SLC5A11抗体对胶质母细胞瘤样本进行免疫组化分析，发现SLC5A11高表达与肿瘤侵袭性和患者预后不良相关，提示其作为潜在治疗靶点。
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**注意**：以上文献为示例，实际研究中建议通过PubMed、Google Scholar等平台以关键词“SLC5A11 antibody”或“SLC5A11 + 应用领域(如cancer, diabetes)”检索最新文献。若需具体文章，可提供更详细的研究背景进一步筛选。
The SLC5A11 antibody is a tool used to detect and study the solute carrier family 5 member 11 (SLC5A11), a sodium-coupled transporter protein encoded by the *SLC5A11* gene. SLC5A11. also known as sodium-coupled monocarboxylate transporter 2 (SMCT2), facilitates the transport of monocarboxylates (e.g., lactate, pyruvate, and short-chain fatty acids) across cell membranes in a sodium-dependent manner. It is expressed in various tissues, including the brain, kidney, and intestine, and plays roles in metabolic homeostasis, nutrient absorption, and cellular energy balance.
Antibodies targeting SLC5A11 are essential for investigating its expression patterns, subcellular localization, and functional regulation in physiological and pathological contexts. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence. Research involving SLC5A11 antibodies has shed light on its potential involvement in diseases such as cancer, neurological disorders, and metabolic syndromes, where altered monocarboxylate transport may impact cellular metabolism or signaling pathways.
These antibodies are typically validated for specificity and sensitivity, often generated in hosts like rabbits or mice using immunogenic peptide sequences. Their application helps unravel SLC5A11's interaction networks, tissue-specific roles, and therapeutic relevance, making them valuable in both basic research and preclinical studies targeting transporter-related pathologies.
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