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Rabbit Polyclonal STK32C Antibody

  • 中文名: STK32C抗体
  • 别    名: PKE; YANK3
货号: IPDX12253
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/20-1/100 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/1000-1/2000 Human,Mouse,Rat

产品详情

AliasesPKE; YANK3
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human STK32C
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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参考文献

以下是关于STK32C抗体的模拟参考文献示例(请注意,这些文献为虚构示例,实际研究中请以真实文献为准):

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1. **文献名称**: "Characterization of STK32C-Specific Antibodies for Kinase Activity Studies"

**作者**: Smith J, et al.

**摘要**: 本研究开发了一种高特异性兔源多克隆抗体,靶向人源STK32C激酶结构域。通过免疫印迹和免疫沉淀实验验证抗体有效性,并发现STK32C在神经元分化中可能通过磷酸化下游底物调控细胞周期。

2. **文献名称**: "STK32C Expression Profiling in Mouse Tissues Using a Novel Monoclonal Antibody"

**作者**: Chen L, et al.

**摘要**: 报道了一种小鼠单克隆抗体(克隆号:3A8),用于检测STK32C在小鼠脑组织和睾丸中的高表达。免疫组化结果显示STK32C可能参与神经突触可塑性和生殖细胞发育调控。

3. **文献名称**: "The Role of STK32C in Cancer: Antibody-Based Detection and Functional Analysis"

**作者**: Gupta R, et al.

**摘要**: 利用商业化STK32C抗体(货号:ABX-1023)分析其在乳腺癌细胞系中的表达,发现STK32C过表达与ERK信号通路激活相关,提示其可能作为癌症治疗的潜在靶点。

4. **文献名称**: "Phosphorylation-Dependent Antibody Reveals STK32C Autoregulatory Mechanism"

**作者**: Tanaka K, et al.

**摘要**: 设计了一种针对STK32C自身磷酸化位点(Ser-205)的抗体,揭示STK32C通过自磷酸化负反馈调节其激酶活性,为相关遗传疾病机制研究提供工具。

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如需真实文献,建议在 **PubMed** 或 **Google Scholar** 中检索关键词“STK32C antibody”或“STK32C kinase”,并筛选近年发表的实验性研究。部分商业化抗体厂商(如Abcam、Santa Cruz)的技术文档也可能提供应用参考文献。

背景信息

The STK32C (Serine/Threonine Kinase 32C) antibody is a tool used to study the STK32C protein, encoded by the STK32C gene in humans. STK32C belongs to the serine/threonine kinase family, which regulates cellular processes like signal transduction, cell cycle progression, and apoptosis. While its exact biological functions remain under investigation, STK32C is hypothesized to play roles in cell differentiation, tissue development, and possibly neurological or metabolic pathways. It shares structural homology with other kinases but exhibits unique substrate specificity due to divergent regulatory domains.

Antibodies targeting STK32C are typically developed in immunized hosts (e.g., rabbits or mice) using purified recombinant protein fragments or synthetic peptides. These antibodies enable detection of STK32C in techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Validation often includes knockout cell lines or tissue controls to confirm specificity. Research applications focus on mapping STK32C expression patterns across tissues, exploring its involvement in diseases like cancer or neurodegenerative disorders, and deciphering its interaction networks. Limited clinical data exist, but its kinase activity suggests potential as a therapeutic target. Current studies prioritize elucidating its physiological substrates and regulatory mechanisms.

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