| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | MNB; DYRK; HP86; MNBH; MRD7; DYRK1 |
| WB Predicted band size | 85 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human DYRK1A |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇关于DYRK1A抗体的代表性文献概览(文献名称、作者及摘要核心内容)：
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1. **文献名称**: "DYRK1A inhibitors as potential therapeutics for Alzheimer's disease"
**作者**: Smith A et al. (2021)
**摘要**: 研究报道了一种新型DYRK1A特异性抗体的体外筛选方法，证实其能有效抑制DYRK1A激酶活性，减少tau蛋白异常磷酸化，为阿尔茨海默病中tau病理机制提供了干预策略。
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2. **文献名称**: "Structural basis of DYRK1A autoinhibition and its inhibition by monoclonal antibodies"
**作者**: Chen L & Wang Y (2020)
**摘要**: 通过冷冻电镜解析DYRK1A蛋白的自抑制构象，并开发靶向其活性位点的单克隆抗体，实验证明该抗体可阻断DYRK1A与底物结合，为唐氏综合症相关认知障碍的治疗提供新思路。
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3. **文献名称**: "Antibody-mediated targeting of DYRK1A in pancreatic cancer models"
**作者**: Rodriguez M et al. (2019)
**摘要**: 开发了一种人源化抗DYRK1A抗体，在胰腺癌小鼠模型中显著抑制肿瘤生长，机制涉及阻断DYRK1A介导的Wnt/β-catenin信号通路激活，提示其作为癌症靶向治疗的潜力。
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(注：以上文献名为虚拟示例，实际文献需通过PubMed/Google Scholar检索关键词如“DYRK1A antibody”或结合具体研究领域筛选。)
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