关键信息
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基因名
RAB32
- 应用
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别名
RAB32;Ras-related Protein Rab-32
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13637
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表达区间
1-225aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSHMAGGGAGDPGLGAAAAPAPETREHLF KVLVIGELGVGKTSIIKR YVHQLFSQHYRATIGVDFALKVLNWDSRTL VRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLK WKS DLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFE TSAKDNINIEEAARFLVEKILV NHQSFPNEENDVDKIKLDQETLRAEN KSQCC
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分子量
28 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
RAB32 is a member of the RAB family of small GTPases, which are critical regulators of intracellular trafficking and membrane dynamics. This protein has garnered attention due to its involvement in various cellular processes, including organelle biogenesis, mitochondrial dynamics, and autophagy. Recent studies have highlighted RAB32's role in the regulation of melanosome transport in melanocytes, suggesting its importance in pigmentation and skin physiology. Furthermore, dysregulation of RAB32 has been implicated in several pathological conditions, including cancer and neurodegenerative diseases. Researchers have been focusing on characterizing RAB32 through recombinant protein technology to elucidate its specific functions and interactions within the cell. The generation of RAB32 recombinant proteins allows for advanced biophysical and biochemical analyses, facilitating the understanding of its mechanism of action in cellular trafficking. As such, RAB32 represents a promising target for therapeutic intervention in diseases where intracellular transport is disrupted. Understanding RAB32's function may provide insights into the development of novel strategies for the treatment of related disorders, making it a topic of significant interest in cell biology and medical research.
