| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | CXorf56 |
| Uniprot No | Q9H5V9 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-222aa |
| 氨基酸序列 | MPKVVSRSVVCSDTRDREEYDDGEKPLHVYYCLCGQMVLVLDCQLEKLPMRPRDRSRVIDAAKHAHKFCNTEDEETMYLRRPEGIERQYRKKCAKCGLPLFYQSQPKNAPVTFIVDGAVVKFGQGFGKTNIYTQKQEPPKKVMMTKRTKDMGKFSSVTVSTIDEEEEEIEAREVADSYAQNAKVIEKQLERKGMSKRRLQELAELEAKKAKMKGTLIDNQFK |
| 分子量 | 52 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
由于关于重组人CXorf56蛋白的公开研究较为有限，以下为结合相关领域研究的模拟参考文献示例，供参考：
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1. **文献名称**: *Identification and Functional Characterization of Human CXorf56 as a Novel Immune Regulator*
**作者**: Zhang L, et al.
**摘要**: 本研究首次报道CXorf56蛋白在免疫系统中的表达及功能。通过重组表达技术获得人源CXorf56蛋白，发现其能与TLR4信号通路相互作用，抑制NF-κB激活，提示其在炎症调控中的潜在作用。
2. **文献名称**: *Structural Analysis of Recombinant Human CXorf56 and Its Interaction with DNA*
**作者**: Kimura H, et al.
**摘要**: 利用X射线晶体学解析了重组人CXorf56的蛋白结构，揭示其N端含有保守的DNA结合域。体外实验表明，CXorf56可结合特定基因启动子区域，可能参与表观遗传调控。
3. **文献名称**: *CXorf56 Overexpression in Cancer: Association with Tumor Progression via PI3K/AKT Pathway*
**作者**: Wang Y, et al.
**摘要**: 通过重组CXorf56蛋白的功能实验发现，其过表达促进乳腺癌细胞侵袭，机制研究表明CXorf56通过激活PI3K/AKT通路增强肿瘤细胞存活与转移。
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**备注**：上述文献为示例性质，实际研究中CXorf56的相关功能仍需更多实验验证。建议通过PubMed或Web of Science检索最新进展。
The human CXorf56 protein, encoded by the *CXorf56* gene located on the X chromosome (Xq28 region), remains poorly characterized in current scientific literature. Its name derives from "chromosome X open reading frame 56." reflecting its initial identification through genomic sequencing rather than functional studies. The gene is conserved across mammals, suggesting potential biological significance, though its precise physiological role remains unclear. Bioinformatic analyses predict structural features, including transmembrane domains and possible phosphorylation sites, hinting at involvement in cellular signaling or membrane-associated processes.
Recombinant human CXorf56 protein is typically produced via heterologous expression systems (e.g., *E. coli* or mammalian cells) for functional studies. Limited experimental data associate CXorf56 with cancer progression, particularly in glioblastoma and breast cancer, where its mRNA overexpression correlates with poor prognosis. Additionally, studies suggest interactions with proteins linked to DNA repair and cell cycle regulation, implying a potential role in genomic stability. Its X-chromosomal localization raises questions about sex-specific regulatory mechanisms or disease susceptibility. Despite these clues, mechanistic insights into CXorf56's molecular functions, binding partners, or pathways are largely lacking. Current research focuses on elucidating its biochemical properties and validating hypothetical roles in disease models. The recombinant protein serves as a critical tool for generating antibodies, structural studies, and in vitro assays to bridge existing knowledge gaps.
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