| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | CXorf6 |
| Uniprot No | Q13495 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-774aa |
| 氨基酸序列 | MDDWKSRLVI KSMLPHFAMV GNRQEPRKLQ ESGKKPSWME EEDLSFLYKS SPGRKHQGTV KRRQEEDHFQ FPDMADGGYP NKIKRPCLED VTLAMGPGAH PSTACAELQV PPLTINPSPA AMGVAGQSLL LENNPMNGNI MGSPFVVPQT TEVGLKGPTV PYYEKINSVP AVDQELQELL EELTKIQDPS PNELDLEKIL GTKPEEPLVL DHPQATLSTT PKPSVQMSHL ESLASSKEFA SSCSQVTGMS LQIPSSSTGI SYSIPSTSKQ IVSPSSSMAQ SKSQVQAMLP VALPPLPVPQ WHHAHQLKAL AASKQGSATK QQGPTPSWSG LPPPGLSPPY RPVPSPHPPP LPLPPPPPPF SPQSLMVSCM SSNTLSGSTL RGSPNALLSS MTSSSNAALG PAMPYAPEKL PSPALTQQPQ FGPQSSILAN LMSSTIKTPQ GHLMSALPAS NPGPSPPYRP EKLSSPGLPQ QSFTPQCSLI RSLTPTSNLL SQQQQQQQQQ QQANVIFKPI SSNSSKTLSM IMQQGMASSS PGATEPFTFG NTKPLSHFVS EPGPQKMPSM PTTSRQPSLL HYLQQPTPTQ ASSATASSTA TATLQLQQQQ QQQQQQPDHS SFLLQQMMQQ PQRFQRSVAS DSMPALPRQG CCHLFAWTSA ASSVKPQHQH GNSFTSRQDP QPGDVSPSNI THVDKACKLG EARHPQVSLG RQPPSCQALG SESFLPGSSF AHELARVTSS YSTSEAAPWG SWDPKAWRQV PAPLLPSCDA TARGTEIRSY GNDP |
| 分子量 | 83.2 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是3篇关于重组人CXorf6蛋白的文献概览(内容为虚构，供参考)：
1. **文献名称**：《重组人CXorf6蛋白的克隆表达及功能研究》
**作者**：Zhang L, et al.
**摘要**：本研究成功构建了重组人CXorf6蛋白的原核表达系统，验证其在小鼠胚胎干细胞分化中的潜在调控作用。
2. **文献名称**：《CXorf6在X染色体失活中的表观遗传调控机制》
**作者**：Wang Y, et al.
**摘要**：通过重组CXorf6蛋白与XIST RNA的互作实验，揭示了其对X染色体失活相关基因的调控途径。
3. **文献名称**：《CXorf6蛋白与卵巢癌增殖的关联研究》
**作者**：Chen R, et al.
**摘要**：利用重组CXorf6蛋白体外实验，发现其过表达可通过调控PI3K/AKT通路抑制卵巢癌细胞增殖。
**备注**：以上文献为模拟示例，具体研究请通过PubMed或Google Scholar以实际关键词检索。若需真实文献推荐，建议补充蛋白功能或疾病背景等信息。
Recombinant human CXorf6 protein is derived from the CXorf6 gene (Chromosome X Open Reading Frame 6), located on the X chromosome. The gene’s function remains partially characterized, though studies suggest it may play roles in transcriptional regulation, cell signaling, and chromatin modification. It has drawn interest due to its potential involvement in X-linked disorders, cancer progression, and neurodevelopmental conditions, with some evidence linking abnormal expression to tumorigenesis and immune dysregulation.
Recombinant CXorf6 is typically produced using prokaryotic or eukaryotic expression systems (e.g., E. coli, HEK293 cells) to enable functional studies. Its production allows researchers to investigate protein-protein interactions, enzymatic activities, and cellular pathways, addressing challenges posed by endogenous CXorf6’s low natural abundance. Current applications include exploring its role in DNA repair, epigenetic modulation, and as a biomarker in cancers like glioblastoma or leukemia.
Despite progress, the protein’s precise molecular mechanisms and physiological relevance remain understudied. Ongoing research focuses on resolving its structure, post-translational modifications, and tissue-specific functions, with recombinant variants serving as critical tools for therapeutic target validation and mechanistic elucidation in both basic and translational contexts.
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