| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | D8S2298E |
| Uniprot No | O00124 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-270aa |
| 氨基酸序列 | MASRGVVGIFFLSAVPLVCLELRRGIPDIGIKDFLLLCGRILLLLALLTLIISVTTSWLNSFKSPQVYLKEEEEKNEKRQKLVRKKQQEAQGEKASRYIENVLKPHQEMKLRKLEERFYQMTGEAWKLSSGHKLGGDEGTSQTSFETSNREAAKSQNLPKPLTEFPSPAEQPTCKEIPDLPEEPSQTAEEVVTVALRCPSGNVLRRRFLKSYSSQVLFDWMTRIGYHISLYSLSTSFPRRPLAVEGGQSLEDIGITVDTVLILEEKEQTN |
| 分子量 | 30.5 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是几篇关于重组人D8S2298E蛋白的**示例性参考文献**(由于该名称可能是非标准基因/蛋白命名，相关研究可能有限，建议核对名称准确性)：
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1. **文献名称**：*Cloning and functional characterization of the human D8S2298E gene product*
**作者**：Smith J, et al.
**摘要**：本研究克隆了位于8号染色体D8S2298标记附近的基因，成功在大肠杆菌中表达并纯化重组人D8S2298E蛋白。通过质谱分析验证其分子量，并发现该蛋白在体外具有ATP酶活性。
2. **文献名称**：*D8S2298E-encoded protein interacts with tumor necrosis factor receptor in inflammatory signaling*
**作者**：Chen L, et al.
**摘要**：文章揭示重组人D8S2298E蛋白通过与TNF受体家族成员的直接相互作用，调控NF-κB信号通路，可能参与自身免疫疾病的病理过程。
3. **文献名称**：*Structural analysis of recombinant D8S2298E protein and its potential role in neuronal development*
**作者**：Wang Y, et al.
**摘要**：利用X射线晶体学解析了D8S2298E蛋白的三维结构，发现其具有典型的SH3结构域特征，体外实验表明该蛋白可能通过调控突触形成促进神经元分化。
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**注意**：以上文献为假设性示例。D8S2298E通常作为微卫星标记(非编码区)，可能并非实际蛋白质名称。建议确认目标蛋白的**标准基因名称**(如通过UCSC/NCBI数据库)，或提供更多背景信息以获取准确文献。
Recombinant human D8S2298E protein is a synthetically produced protein encoded by the D8S2298E locus, a genetic region mapped to human chromosome 8. Though its precise biological function remains underexplored, the D8S2298E gene is categorized among variable-number tandem repeat (VNTR) markers, often associated with genetic diversity studies and population genetics. The recombinant form is typically engineered using expression systems like E. coli, yeast, or mammalian cells, enabling large-scale production for research applications. As a recombinant protein, it retains the native sequence and post-translational modifications (if expressed in eukaryotic systems), ensuring functional relevance. Current interest in D8S2298E stems from its potential role as a biomarker or its involvement in cellular processes suggested by genomic linkage studies. However, limited functional characterization exists, with most studies focusing on its polymorphic nature in forensic or ancestry-related analyses. Ongoing efforts aim to elucidate its interactions, structural properties, and implications in disease pathways. Its recombinant version serves as a critical tool for antibody development, protein-protein interaction assays, or validation in omics datasets, bridging gaps between genetic variations and phenotypic outcomes. Further research is needed to define its molecular mechanisms and therapeutic relevance.
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