Cat: PA2000-5546

Recombinant Human APOL5 Protein,His

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关键信息

  • 基因名

    APOL5

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    APOL5ApolipoProtein L5; ApolipoProtein L-V; ApoL-V

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9BWW9

  • 表达区间

    1-433aa

  • 氨基酸序列

    MPCGKQGNLQ VPGSKVLPGL GEGCKEMWLR KVIYGGEVWG KSPEPEFPSL VNLCQSWKIN NLMSTVHSDE AGMLSYFLFE ELMRCDKDSM PDGNLSEEEK LFLSYFPLHK FELEQNIKEL NTLADQVDTT HELLTKTSLV ASSSGAVSGV MNILGLALAP VTAGGSLMLS ATGTGLGAAA AITNIVTNVL ENRSNSAARD KASRLGPLTT SHEAFGGINW SEIEAAGFCV NKCVKAIQGI KDLHAYQMAK SNSGFMAMVK NFVAKRHIPF WTARGVQRAF EGTTLAMTNG AWVMGAAGAG FLLMKDMSSF LQSWKHLEDG ARTETAEELR ALAKKLEQEL DRLTQHHRHL PQKASQTCSS SRGRAVRGSR VVKPEGSRSP LPWPVVEHQP RLGPGVALRT PKRTVSAPRM LGHQPAPPAP ARKGRQAPGR HRQ

  • 分子量

    47.0 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

APOL5 (Apolipoprotein L5) is a member of the apolipoprotein family, which plays a crucial role in lipid metabolism, immune response, and the transport of various biomolecules. Recent studies have highlighted the potential significance of APOL5 in the context of several diseases, including cardiovascular disorders, inflammation, and certain infections. The gene encoding APOL5 is located on chromosome 22 and exhibits expression primarily in the liver and other tissues involved in energy homeostasis. Notably, APOL5 stands out due to its involvement in the modulation of immune responses against parasites and its potential role in host defense mechanisms. In light of its various biological functions, researchers are increasingly interested in characterizing the recombinant APOL5 protein to better understand its properties and interactions. The recombinant protein production allows for detailed studies on protein structure, function, and its mechanisms of action, facilitating the exploration of APOL5 as a therapeutic target or biomarker. Furthermore, by examining its interactions with lipids and other proteins, scientists aim to delineate its role in metabolic pathways and disease processes, with the ultimate goal of advancing our knowledge of its potential implications in human health and disease.

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