| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FAM102B |
| Uniprot No | Q5T8I3 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-329aa |
| 氨基酸序列 | MRLLDGGSFTAESSREVVQANCVRWRKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTTRRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTPPSTSMSIPIAGESESLQEDRKGGETLKVHLGIADLSAKSASVPDELGACGHSRTSSYASQQSKVSGYSTCHSRSSSFSELCHRRNTSVGSTSTGVESILEPCDEIEQKIAEPNLDTADKEDTASEKLSRCPVKQDSVESQLKRVDDTRVDADDIVEKILQSQDFSLDSSAEEEGLRLFVGPGGSTTFGSHHLPNRVGSGAYEQVVIKR |
| 分子量 | 62 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下为虚构的参考文献示例，供参考(实际文献请通过学术数据库检索获取)：
1. **"Expression and Purification of Recombinant Human FAM102B in E. coli"**
*作者：Zhang et al.*
摘要：本文报道了通过大肠杆菌表达系统高效表达重组人FAM102B蛋白，并优化了纯化条件，利用Ni-NTA亲和层析获得高纯度蛋白，为后续功能研究奠定基础。
2. **"Functional Characterization of FAM102B as a Phospholipid-Binding Protein in Neuronal Cells"**
*作者：Chen & Wang*
摘要：研究利用重组人FAM102B蛋白验证其与细胞膜磷脂的结合能力，发现其通过PH结构域参与神经元突触的信号转导，可能影响突触可塑性。
3. **"Structural Insights into FAM102B Revealed by X-ray Crystallography"**
*作者：Gupta et al.*
摘要：通过X射线晶体学解析了重组人FAM102B蛋白的三维结构，揭示了其独特的α/β折叠模式及潜在底物结合位点，为疾病相关突变分析提供结构基础。
4. **"FAM102B Interacts with Tumor Suppressor p53: A Yeast Two-Hybrid Screening Study"**
*作者：Li et al.*
摘要：利用重组FAM102B筛选相互作用蛋白，发现其与p53直接结合，可能通过调控p53稳定性参与癌症细胞凋亡通路。
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**注意**：以上文献及内容均为模拟创作，实际研究可能有限。建议使用关键词“recombinant FAM102B”“FAM102B function”在PubMed、Web of Science等平台检索最新文献。
**Background of Recombinant Human FAM102B Protein**
Recombinant human FAM102B protein is a genetically engineered version of the FAM102B (Family With Sequence Similarity 102 Member B) protein, encoded by the *FAM102B* gene. This protein, also known as C1orf123. is a member of the evolutionarily conserved FAM102 family, characterized by a conserved domain of unknown function (DUF1724). FAM102B is widely expressed in human tissues, including the brain, testis, and liver, and is implicated in intracellular signaling, vesicular trafficking, or cytoskeletal regulation, though its precise biological functions remain unclear.
Studies suggest potential roles in cellular stress responses and interactions with other regulatory proteins. Recombinant FAM102B is typically produced in *E. coli* or mammalian expression systems, enabling studies on its structure, post-translational modifications, and functional mechanisms. Its recombinant form is crucial for investigating binding partners, enzyme activities, or involvement in pathways like Wnt signaling.
Research interest in FAM102B has grown due to its potential links to cancers, neurodegenerative diseases, or developmental disorders. However, functional characterization remains limited, highlighting the need for further exploration. Recombinant FAM102B serves as a vital tool for unraveling its physiological and pathological roles, supporting drug discovery and therapeutic targeting efforts.
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