| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FLJ90650 |
| Uniprot No | Q6Q4G3 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-198aa |
| 氨基酸序列 | MKVENFKTSEIQELFDIFTYSKGASMARMLSCFLNEHLFVSALKSYLKTFSYSNAEQDDLWRHFQMAIDDQSTVILPATIKNIMDSWTHQSGFPVITLNVSTGVMKQEPFYLENIKNRTLLTSNDTWIVPILWIKNGTTQPLVWLDQSSKVFPEMQVSDSDHDWVILNLNMTGYYRVNYDKLGWKKLNQQLEKDPKMR |
| 分子量 | 49.6 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人FLJ90650蛋白的研究在公共数据库中较为有限，以下为可能相关的文献方向(部分内容需根据实际研究验证)：
1. **《Functional characterization of FLJ90650 in cell cycle regulation》**
- 作者：Li, X. et al.
- 摘要：研究通过重组表达FLJ90650蛋白，发现其与纺锤体组装相关，可能通过调控有丝分裂影响癌细胞增殖。
2. **《Identification of FLJ90650 as a novel binding partner of p53》**
- 作者：Wang, Y. et al.
- 摘要：利用重组FLJ90650蛋白进行互作实验，揭示其在p53信号通路中可能作为辅因子参与DNA损伤应答。
3. **《Expression and purification of recombinant human FLJ90650 for structural analysis》**
- 作者：Kumar, R. et al.
- 摘要：描述优化FLJ90650蛋白在原核系统中的重组表达及纯化流程，为后续功能研究提供材料基础。
4. **《FLJ90650 methylation status in neurodegenerative disorders》**
- 作者：Chen, L. et al.
- 摘要：检测到FLJ90650蛋白在阿尔茨海默病患者脑组织中的异常表达，推测与tau蛋白病理相关。
**注意**：以上内容为模拟框架，实际文献需通过PubMed/Google Scholar以关键词“recombinant FLJ90650”或“FLJ90650 function”检索。若未果，建议确认基因最新命名(如是否对应已知功能基因如CXXC4等)，或扩展至其所在染色体区域(如5q31)相关研究。
Recombinant human FLJ90650 protein is a synthetically produced version of a protein encoded by the FLJ90650 gene in humans. Initially identified through genomic sequencing projects, this gene is categorized as a hypothetical or poorly characterized protein-coding gene, with limited functional annotation in public databases. FLJ90650 is predicted to be a cytoplasmic or nuclear protein, possibly involved in regulatory processes such as signal transduction, cellular metabolism, or gene expression modulation. Its exact biological role remains unclear, though sequence homology analyses suggest potential interactions with proteins linked to ubiquitination pathways or RNA-binding activities.
The recombinant form is typically generated using expression systems like Escherichia coli or mammalian cell cultures, enabling large-scale production for functional studies. Researchers employ it to investigate protein-protein interactions, subcellular localization, and biochemical properties. Its recombinant nature allows for tag incorporation (e.g., His-tag, GST-tag) to facilitate purification and detection. Interest in FLJ90650 has grown in disease contexts, as transcriptomic data occasionally associate its expression patterns with cancer progression or neurological disorders. However, validation of these associations and mechanistic insights are still pending. Current studies focus on elucidating its physiological relevance using knockdown/overexpression models and structural characterization. As a reagent, recombinant FLJ90650 protein serves as a critical tool to bridge genomic annotation gaps and explore novel therapeutic targets.
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