关键信息
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基因名
YEATS4
- 应用
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别名
YEATS4；GAS41；YEATS domain-containing Protein 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95619
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表达区间
1-227aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMFKRMAEFGPDSGGRVKGVTIVKPIVY GNVARYFGKKREEDGHTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNP LRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKLFQSDTNA MLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEV KTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKDI
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分子量
29 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
YEATS4 is a member of the YEATS domain-containing protein family, which has emerged as a significant player in the regulation of gene expression and chromatin remodeling. Recent studies have indicated that YEATS4 is involved in various biological processes, including transcriptional regulation and the response to environmental stimuli. Its unique YEATS domain has been shown to bind to acetylated lysines, suggesting a role in recognizing and interpreting histone modifications, which are critical for the proper functioning of chromatin. Dysregulation of YEATS4 has been implicated in several diseases, including cancer, where altered gene expression profiles can lead to tumorigenesis. Therefore, the study of YEATS4 and its recombinant protein forms is essential for understanding its molecular mechanisms and biological significance. By utilizing recombinant DNA technology, researchers aim to produce and characterize the YEATS4 protein, facilitating investigations into its structure, binding interactions, and functional roles in cellular processes. This knowledge could provide insights into the development of therapeutic strategies targeting YEATS4-related pathways in diseases where its function is compromised. The comprehensive understanding of YEATS4’s role may pave the way for novel approaches in cancer treatment and the manipulation of gene expression for therapeutic benefits.
