| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | TEX13A |
| Uniprot No | Q9BXU3 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-409 aa |
| 活性数据 | MALRPEDPSS GFRHSNVVAF INEKMARHTK GPEFYLENIS LSWEKVEDKL RAILEDSEVP SEVKEACTWG SLALGVRFAH RQAQLQRHRV RWLHGFAKLH KSAAQALASD LKKLREQQET ERKEAASRLR MAQTSLVEVQ KERDKELVSP HEWEQGAGWP GLATAGGVCT EGAAEEEEEA AVAAAGAAGG KGAEEEQRDV EVVAAPVEAM APPVEAGAAP METQFPHVEA RAASMETTEK LERILLQLLG DADQEKYTYW GQKEGDLRSV ETATSYFSGT TNPWSRASSE PLPVQLPASY SYSYSSPFSS FSDIPTISPP QATVTAPVPP QLPSDWEAFD TSLWSDGGPH RIDHQEHPRD RRYSEPHQQR PPVYRRPGDW DCPWCNAVNF SRRDTCFDCG KGIWLQKPH |
| 分子量 | 45.5 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人TEX13A蛋白的3-4篇参考文献的示例总结(部分信息为模拟虚构，实际文献需通过数据库验证)：
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1. **文献名称**: *Cloning and Characterization of Human TEX13A: A Testis-Specific Gene Encoding a Novel Chromobox Family Protein*
**作者**: Li, Y. et al.
**摘要**: 该研究成功克隆并在HEK293细胞中重组表达了人TEX13A蛋白，发现其含保守的染色质结合结构域，可能参与减数分裂过程中染色质重塑，为生殖细胞发育机制提供了新线索。
2. **文献名称**: *TEX13A Interacts with piRNA Pathway Proteins and Associates with Male Infertility*
**作者**: Chen, J. et al.
**摘要**: 通过免疫共沉淀和质谱分析，发现重组TEX13A蛋白与piRNA通路蛋白互作，临床数据显示其在部分少精症患者中表达异常，提示其可能参与精子发生调控。
3. **文献名称**: *Structural Prediction and Evolutionary Analysis of the TEX13A Protein Across Species*
**作者**: Gupta, R. & Singh, S.
**摘要**: 利用生物信息学方法预测TEX13A蛋白的三维结构，揭示其N端具有跨膜螺旋，可能在物种进化中高度保守，为后续功能研究提供结构基础。
4. **文献名称**: *Expression Profiling of TEX13A in Normal and Cancer Tissues*
**作者**: Wang, X. et al.
**摘要**: 通过免疫组化分析重组TEX13A蛋白的表达模式，发现除睾丸组织外，其在乳腺癌和肝癌中异常高表达，提示其潜在致癌作用。
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**备注**：以上文献为示例模板，实际研究中请通过PubMed、Google Scholar或Web of Science等平台检索**真实文献**(如以“TEX13A recombinant protein”为关键词)。部分条目可能需结合其他生殖相关蛋白研究推断内容。
TEX13A (testis-expressed protein 13A) is a human protein encoded by the TEX13A gene, which belongs to the TEX gene family predominantly expressed in the testis. This family is associated with germ cell development, meiosis, and spermatogenesis. TEX13A is evolutionarily conserved and contains a conserved domain of unknown function (DUF3729), suggesting potential roles in molecular interactions or cellular processes specific to germ cells. Although its precise biological function remains unclear, studies indicate that TEX13A is localized to the nucleus and may participate in chromatin remodeling, RNA metabolism, or transcriptional regulation during gametogenesis.
Recombinant TEX13A protein is typically produced using expression systems like Escherichia coli or mammalian cells, followed by purification via affinity chromatography for research applications. Its recombinant form enables functional studies to explore its involvement in male fertility, as knockout models or mutations in TEX genes often lead to sterility. Research on TEX13A also extends to understanding its potential association with germ cell tumors or disorders of sexual development. Additionally, structural analysis of recombinant TEX13A could clarify its biochemical properties and interaction networks. Investigating this protein contributes to broader insights into reproductive biology and may inform therapeutic strategies for infertility or contraceptive development.
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