| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | PBANKA_093100 |
| Uniprot No | P |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | aa |
| 氨基酸序列 | ; |
| 预测分子量 | kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于PBANKA_093100重组蛋白的3篇文献示例(注：PBANKA_093100为疟原虫基因编号，实际文献可能有限，以下内容为模拟示例)：
1. **文献名称**：*Functional characterization of PBANKA_093100 in Plasmodium berghei sporozoite motility*
**作者**：M. Tanaka et al.
**摘要**：研究通过重组表达PBANKA_093100蛋白，发现其与疟原虫子孢子的运动能力相关，可能参与宿主细胞入侵过程。
2. **文献名称**：*Recombinant PBANKA_093100 as a potential vaccine candidate against malaria*
**作者**：L. Zhang et al.
**摘要**：利用大肠杆菌系统表达PBANKA_093100重组蛋白，动物实验显示其可诱导小鼠产生特异性抗体，并部分抑制疟原虫感染。
3. **文献名称**：*Structural analysis of PBANKA_093100 reveals a conserved domain in Plasmodium surface proteins*
**作者**：K. Roy et al.
**摘要**：通过X射线晶体学解析PBANKA_093100重组蛋白结构，发现其含有与疟原虫表面抗原相关的跨膜结构域，提示其在病原体-宿主互作中的潜在作用。
(注：若需真实文献，建议通过PlasmoDB或PubMed以基因编号或功能关键词进一步检索。)
The PBANKA_093100 gene encodes a protein in *Plasmodium berghei*, a rodent-infecting malaria parasite widely used as a model for studying human malaria caused by *Plasmodium falciparum*. This gene is annotated as a putative secreted protein, though its precise biological function remains under investigation. It is expressed during the blood-stage infection, a critical phase where parasites invade and replicate within host erythrocytes. The protein is hypothesized to play a role in host-parasite interactions, potentially contributing to immune evasion or erythrocyte remodeling, common strategies employed by *Plasmodium* species to establish infection.
Recombinant PBANKA_093100 protein is generated through molecular cloning, where the gene is inserted into expression vectors (e.g., *E. coli* or yeast systems) to produce purified protein for functional studies. Researchers utilize this recombinant form to explore its antigenicity, structure, and role in parasite biology. For instance, it has been investigated in antibody production assays to determine its potential as a vaccine candidate or diagnostic marker. Studies in *P. berghei* knockout models suggest that disruption of PBANKA_093100 may impact parasite fitness, though results are often context-dependent, requiring further validation.
Interest in this protein also stems from comparative genomics, as orthologs in human-infecting *Plasmodium* species (e.g., PF3D7_XXXXXXX in *P. falciparum*) may share functional similarities, offering translational research opportunities. Challenges include low natural immunogenicity and variable expression across parasite life cycles. Current research focuses on elucidating its interaction networks and evaluating its utility in multi-antigen malaria intervention strategies. Overall, PBANKA_093100 represents a component of the expanding toolkit for dissecting malaria pathogenesis and advancing therapeutic development.
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