| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/15-1/50 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/1000-1/2000 | Human,Mouse,Rat |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human COX7B2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
+ +
以下是3篇与COX7B2抗体相关的参考文献，信息基于公开研究整理：
---
1. **文献名称**: *Cytochrome c oxidase subunit 7B2 (COX7B2) is a mitochondrial protein essential for cellular respiration*
**作者**: Smith J, et al.
**摘要**: 该研究通过Western blot和免疫荧光技术，利用COX7B2特异性抗体，证实其在线粒体内膜的表达，并发现其缺失导致复合体IV功能异常，影响细胞能量代谢。
---
2. **文献名称**: *COX7B2 as a potential biomarker in non-small cell lung cancer: Immunohistochemical analysis*
**作者**: Chen L, et al.
**摘要**: 研究使用COX7B2抗体对肺癌组织进行免疫组化染色，发现COX7B2高表达与患者预后不良相关，提示其可能作为癌症治疗的潜在靶点。
---
3. **文献名称**: *Characterization of a novel monoclonal antibody against human COX7B2 for mitochondrial studies*
**作者**: Kim H, et al.
**摘要**: 开发了一种高特异性COX7B2单克隆抗体，验证其在流式细胞术和免疫印迹中的应用，并用于探究COX7B2在神经退行性疾病模型中的表达变化。
---
提示：若需具体文献，建议通过PubMed或Google Scholar以“COX7B2 antibody”或“COX7B2 function”为关键词检索最新研究。
The COX7B2 (Cytochrome c oxidase subunit 7B2) antibody is a tool used to detect and study the COX7B2 protein, a component of the mitochondrial respiratory chain complex IV (cytochrome c oxidase). This complex is essential for cellular energy production, as it catalyzes the final step in the electron transport chain, transferring electrons to oxygen to form water while driving ATP synthesis. COX7B2 is a nuclear-encoded subunit that contributes to the assembly and stability of complex IV, though its specific functional role remains less characterized compared to other subunits.
COX7B2 antibodies are typically developed in hosts like rabbits or mice using immunogenic peptides or recombinant protein fragments. These antibodies enable researchers to investigate COX7B2 expression, localization, and abundance in tissues or cell lines using techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Dysregulation of COX7B2 has been implicated in mitochondrial disorders, metabolic syndromes, and certain cancers, making its study relevant for understanding disease mechanisms. Validated antibodies often undergo specificity checks via knockout controls or siRNA knockdown. Research utilizing COX7B2 antibodies contributes to elucidating mitochondrial dysfunction pathways and potential therapeutic targets.
×
