| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | VWS1; CLICK3; CLICKIII; dJ272L16.1 |
| WB Predicted band size | 53 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human CAMK1G |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于CAMK1G抗体的3篇参考文献示例(内容为模拟，非真实文献)：
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1. **文献名称**：*Characterization of CAMK1G Antibody Specificity in Neuronal Signaling Pathways*
**作者**：Smith A, et al.
**摘要**：本研究验证了一种新型抗CAMK1G抗体的特异性，通过Western blot和免疫荧光技术证明其在人脑组织及神经元细胞系中的高选择性。实验表明CAMK1G在钙离子信号传导中调控突触可塑性，抗体成功用于检测其磷酸化状态。
2. **文献名称**：*CAMK1G Expression in Colorectal Cancer: An Immunohistochemical Study*
**作者**：Chen L, et al.
**摘要**：利用商业化CAMK1G抗体对结直肠癌组织进行免疫组化分析，发现CAMK1G高表达与患者预后不良相关，提示其可能作为肿瘤进展的生物标志物。抗体特异性通过siRNA敲低实验验证。
3. **文献名称**：*Development of a Monoclonal Antibody Targeting CAMK1G for Functional Studies*
**作者**：Yamamoto K, et al.
**摘要**：报道了一种高亲和力CAMK1G单克隆抗体的开发，该抗体适用于流式细胞术和免疫沉淀。研究证实CAMK1G在T细胞活化中调控NFAT信号通路，抗体成功用于体内外功能抑制实验。
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注：以上内容为示例，实际文献需通过PubMed、Google Scholar等平台检索确认。
The CAMK1G antibody is a research tool designed to detect and quantify the calcium/calmodulin-dependent protein kinase 1G (CAMK1G), a member of the CAMK serine/threonine kinase family. CAMK1G is part of the CAMK1 subfamily, which includes kinases activated by calcium/calmodulin signaling. This enzyme plays a role in regulating cellular processes such as transcriptional activation, cell cycle progression, and hormone secretion by phosphorylating downstream targets. Structurally, CAMK1G contains a catalytic domain, an autoinhibitory regulatory domain, and a C-terminal extension that may influence subcellular localization and substrate specificity.
Expressed predominantly in the brain, testis, and endocrine tissues, CAMK1G is implicated in neural development, synaptic plasticity, and endocrine functions. Studies suggest its involvement in pathways linking calcium signaling to gene expression, often interacting with upstream activators like CAMKK and calmodulin. Dysregulation of CAMK1G has been explored in neurological disorders and metabolic syndromes, though its exact pathophysiological roles remain under investigation.
The CAMK1G antibody is widely used in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to study protein expression, localization, and activity in cellular or tissue samples. Researchers rely on its specificity to explore CAMK1G's interactions, activation mechanisms, and relevance in disease models. Validated antibodies are critical for distinguishing CAMK1G from homologous kinases, ensuring accuracy in experimental data. As calcium signaling pathways are central to numerous physiological and pathological processes, CAMK1G antibodies serve as essential tools for advancing understanding of cellular signaling networks.
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