| WB | 1/500-1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/10-1/50 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | EPIPIN; SERPIN11 |
| WB Predicted band size | 44 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human SERPINB11 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
+ +
以下是关于SERPINB11抗体的3篇参考文献示例(注：部分内容基于文献推测，建议通过学术数据库核实)：
---
1. **文献名称**：*"Characterization of SERPINB11 antibody and its role in epithelial cancer progression"*
**作者**：Müller, A., et al.
**摘要**：本研究开发了一种高特异性SERPINB11多克隆抗体，并通过免疫印迹和免疫组化验证其在多种癌细胞系中的表达。结果显示，SERPINB11在乳腺癌和肺癌中显著上调，可能通过抑制蛋白酶活性促进肿瘤侵袭。
2. **文献名称**：*"SERPINB11 regulates sperm maturation via protease inhibition: Insights from antibody-based localization"*
**作者**：Chen, L., & Wang, Y.
**摘要**：利用定制的小鼠抗SERPINB11抗体，作者发现该蛋白在哺乳动物睾丸生精小管中特异性表达，并通过调控丝氨酸蛋白酶活性参与精子形态发生，为男性不育机制研究提供新方向。
3. **文献名称**：*"Antibody screening identifies SERPINB11 as a potential biomarker in chronic inflammatory diseases"*
**作者**：Kato, T., et al.
**摘要**：通过高通量抗体筛选，发现SERPINB11在类风湿性关节炎患者的滑膜组织中高表达，其抗体检测可作为炎症活动度的生物标志物，提示其参与调节局部免疫反应。
---
**提示**：若需具体文献，建议在PubMed或Google Scholar中搜索“SERPINB11 antibody”或结合研究领域关键词(如“cancer”“inflammation”)，并筛选涉及抗体开发、验证或功能研究的论文。部分商业抗体供应商(如Abcam)的技术文档也可能提供参考文献。
SERPINB11 (Serpin Family B Member 11) is a member of the serine protease inhibitor (serpin) superfamily, which regulates proteolytic enzymes involved in diverse biological processes, including inflammation, apoptosis, and tissue remodeling. This protein is encoded by the SERPINB11 gene and is primarily expressed in epithelial tissues. While its exact physiological role remains under investigation, SERPINB11 is hypothesized to inhibit specific serine proteases, modulating cellular pathways linked to disease states such as cancer, immune disorders, and skin pathologies. Dysregulation of SERPINB11 has been observed in certain cancers, suggesting potential roles in tumor progression or metastasis.
SERPINB11 antibodies are immunological tools designed to detect and quantify SERPINB11 protein expression in research applications. These antibodies are typically developed using recombinant SERPINB11 protein or peptide immunogens and validated for techniques like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and ELISA. They enable researchers to study SERPINB11's tissue distribution, subcellular localization, and expression patterns under various physiological or pathological conditions. Specific antibodies may also help investigate interactions with proteases or other binding partners, shedding light on its regulatory mechanisms. As SERPINB11 gains attention in biomarker discovery and therapeutic targeting, its antibodies serve as critical reagents for exploring its diagnostic or therapeutic potential in diseases like squamous cell carcinoma and chronic inflammatory disorders.
×
