Rabbit Polyclonal STX18 Antibody

The STX18 antibody targets Syntaxin 18 (STX18), a member of the SNARE protein family critical for intracellular membrane trafficking. STX18 localizes to the endoplasmic reticulum (ER) and plays a key role in vesicle fusion events, particularly in ER-Golgi transport and autophagy. It interacts with other SNARE proteins, such as Sec22b and BNIP1. to mediate membrane docking and fusion. Antibodies against STX18 are widely used in cell biology research to investigate membrane trafficking pathways, organelle dynamics, and protein-protein interactions. They are essential tools in techniques like Western blotting, immunofluorescence, and immunoprecipitation to study STX18 expression, localization, and function. STX18 dysregulation has been implicated in diseases like cancer and neurodegenerative disorders, driving interest in its mechanistic roles. Commercial STX18 antibodies are typically produced in rabbits or mice, validated for specificity across applications. Research utilizing these antibodies has advanced understanding of cellular homeostasis, secretion, and stress responses linked to ER function. Their continued use supports ongoing exploration of membrane biology and disease mechanisms.