| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | KOX21; ZNF37 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human ZNF37A |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于ZNF37A抗体的虚构参考文献示例(请注意，这些文献并非真实存在，仅供示例参考)：
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1. **文献名称**：*ZNF37A Expression in Human Cancers: Immunohistochemical Analysis*
**作者**：Smith J, et al.
**摘要**：本研究使用特异性ZNF37A抗体，通过免疫组化技术检测其在多种癌症组织中的表达水平，发现ZNF37A在乳腺癌和结直肠癌中显著高表达，并与患者预后不良相关。
2. **文献名称**：*Functional Characterization of ZNF37A in Neuronal Development*
**作者**：Lee H, et al.
**摘要**：通过Western blot和免疫荧光技术，利用ZNF37A抗体揭示其在神经元分化中的动态表达模式，表明ZNF37A可能通过调控突触相关基因参与神经发育。
3. **文献名称**：*Genome-wide Binding Analysis of ZNF37A Using ChIP-seq*
**作者**：Garcia R, et al.
**摘要**：采用ZNF37A特异性抗体进行染色质免疫沉淀测序(ChIP-seq)，鉴定其结合的启动子区域，提示ZNF37A在表观遗传调控中可能靶向细胞周期相关基因。
4. **文献名称**：*ZNF37A Antibody Validation for Flow Cytometry Applications*
**作者**：Chen L, et al.
**摘要**：研究验证了ZNF37A抗体在流式细胞术中的适用性，证明其在检测造血干细胞表面ZNF37A表达时具有高特异性和灵敏度。
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**注意**：上述文献为示例性虚构内容，实际研究中关于ZNF37A抗体的公开文献较为有限。建议通过PubMed或Google Scholar等平台，结合关键词“ZNF37A antibody”或“ZNF37A immunohistochemistry”检索最新研究，并确认基因命名准确性(如是否为ZNF37A或类似名称)。
The ZNF37A antibody is a research tool designed to detect and study the zinc finger protein 37A (ZNF37A), a member of the Krüppel-associated box (KRAB) domain-containing zinc finger protein (ZNF) family. ZNF37A, encoded by the ZNF37A gene in humans, is characterized by tandem C2H2-type zinc finger motifs that facilitate DNA binding, and a KRAB domain implicated in transcriptional repression through interactions with chromatin-modifying complexes. These proteins are thought to play roles in gene regulation, particularly during development, differentiation, and cellular stress responses.
Antibodies targeting ZNF37A are commonly used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to investigate its expression, localization, and function in tissues or cell lines. Their specificity is validated using knockout controls or siRNA-mediated knockdown to confirm binding to the intended target. Commercially available ZNF37A antibodies are often raised in hosts like rabbits or mice, with formats including monoclonal or polyclonal options.
Research on ZNF37A remains limited compared to other ZNF family members, but studies suggest potential roles in oncogenesis or tumor suppression, given the frequent dysregulation of ZNF proteins in cancers. Its expression patterns in specific tissues, such as the brain or reproductive organs, also hint at tissue-specific regulatory functions. However, detailed mechanistic insights into ZNF37A’s biological significance and clinical relevance await further exploration. Proper validation of ZNF37A antibodies remains critical to ensure accurate interpretation of experimental results.
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