| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/30-1/150 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | NUDT20 |
| WB Predicted band size | 48 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human DCP2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于DCP2抗体的3篇参考文献的简要概括(文献为虚构示例，仅作参考)：
1. **文献名称**: "DCP2 as a Novel Diagnostic Biomarker in Hepatocellular Carcinoma: Immunohistochemical Analysis"
**作者**: Li, X. et al.
**摘要**: 本研究通过免疫组化(IHC)和Western blot技术，使用特异性DCP2抗体检测肝细胞癌(HCC)组织中DCP2蛋白的表达水平，发现其过表达与肿瘤进展和不良预后显著相关，提示DCP2可能作为HCC的潜在诊断标志物。
2. **文献名称**: "The Role of DCP2 in mRNA Decapping and Antiviral Immune Response"
**作者**: Wang, Y. et al.
**摘要**: 文章利用DCP2抗体进行免疫共沉淀(Co-IP)和免疫荧光实验，验证了DCP2在细胞质mRNA脱帽复合体中的核心作用，并发现其与病毒RNA降解过程的关联，为抗病毒治疗提供新靶点。
3. **文献名称**: "DCP2 Knockdown Inhibits Colorectal Cancer Metastasis via Regulating mRNA Stability"
**作者**: Smith, J. et al.
**摘要**: 研究通过siRNA敲低DCP2并结合DCP2抗体的Western blot验证，证明DCP2通过调控促癌mRNA的稳定性影响结直肠癌转移，为靶向DCP2的癌症治疗提供依据。
4. **文献名称**: "DCP2 Antibody-Based Detection of Neuronal mRNA Decapping in Neurodegeneration"
**作者**: Nakamura, K. et al.
**摘要**: 通过DCP2抗体进行脑组织切片染色，揭示了DCP2在阿尔茨海默病模型中的异常分布，表明其可能通过调节神经元mRNA代谢参与神经退行性病变机制。
(注：以上文献为模拟内容，实际引用需查询真实数据库如PubMed或Web of Science。)
The DCP2 (Decapping Enzyme 2) antibody is a tool used to study the DCP2 protein, a critical component of the mRNA decapping complex in eukaryotic cells. DCP2 functions as a catalytic subunit within this complex, partnering with DCP1 and other regulatory proteins to remove the protective 5' cap structure from mRNAs, marking them for degradation by exonucleases. This process is essential for regulating mRNA turnover, controlling gene expression, and maintaining cellular homeostasis. DCP2-mediated decapping is tightly regulated and plays a role in diverse biological processes, including stress responses, development, and cell cycle progression.
Antibodies targeting DCP2 enable researchers to investigate its expression levels, subcellular localization, and interactions with other proteins. They are widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to explore how DCP2 contributes to mRNA decay pathways or dysregulation in diseases. For example, altered DCP2 activity has been linked to neurological disorders, cancers, and viral infections, where disrupted mRNA stability may drive pathological processes. By studying DCP2. scientists aim to uncover mechanisms underlying post-transcriptional gene regulation and identify potential therapeutic targets. The DCP2 antibody thus serves as a key reagent in molecular and cellular biology research focused on RNA metabolism and its broader physiological implications.
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