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Rabbit Polyclonal TCEANC2 Antibody

  • 中文名: TCEANC2抗体
  • 别    名: C1orf83
货号: IPDX10049
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/200-1/400 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/5000-1/10000 Human,Mouse,Rat

产品详情

AliasesC1orf83
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human TCEANC2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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参考文献

以下是关于TCEANC2抗体的3篇模拟参考文献示例(注:TCEANC2相关研究较少,部分信息为假设性概括,建议通过学术数据库核实具体文献):

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1. **文献名称**:*TCEANC2 modulates transcriptional regulation in prostate cancer via antibody-specific interactions*

**作者**:Smith J, et al.

**摘要**:本研究利用TCEANC2特异性抗体,揭示了该蛋白在前列腺癌细胞中通过调控转录延伸因子复合体活性,促进肿瘤增殖的机制。抗体通过免疫沉淀和ChIP-seq技术证实了TCEANC2与RNA聚合酶II的相互作用。

2. **文献名称**:*Development and validation of a novel anti-TCEANC2 monoclonal antibody for neurodegenerative disease research*

**作者**:Lee H, et al.

**摘要**:研究团队开发了一种高亲和力的抗TCEANC2单克隆抗体,并验证了其在阿尔茨海默病模型小鼠脑组织中的特异性标记能力。结果显示TCEANC2在神经元DNA损伤修复通路中可能起关键作用。

3. **文献名称**:*TCEANC2 antibody reveals its role in epithelial-mesenchymal transition during cancer metastasis*

**作者**:Garcia R, et al.

**摘要**:通过免疫组化及Western blot分析,本文发现TCEANC2在转移性结直肠癌组织中高表达,其抗体阻断实验表明该蛋白通过调控EMT相关转录因子(如Snail)促进癌细胞侵袭。

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**说明**:若实际研究中TCEANC2抗体文献不足,可扩展检索其所属基因家族(如转录延伸因子相关蛋白)或结合泛癌分析研究。建议使用关键词“TCEANC2 antibody”、“TCEANC2 function”在PubMed或Web of Science进一步筛选。

背景信息

The TCEANC2 antibody targets the TCEANC2 protein, also known as Transcription Elongation Factor A N-Terminal and C-Terminal Domain Containing 2. a less characterized member of the transcription elongation factor family. TCEANC2 is hypothesized to regulate RNA polymerase II-mediated transcription elongation, potentially influencing gene expression by interacting with transcriptional machinery or chromatin-modifying complexes. Although its exact biological role remains unclear, studies suggest involvement in cellular processes like cell cycle regulation and DNA repair. The antibody is primarily utilized in research to detect TCEANC2 expression in various tissues and cell lines via techniques such as Western blotting, immunohistochemistry, and immunofluorescence. Emerging evidence links TCEANC2 dysregulation to diseases, including certain cancers, where altered expression may correlate with tumor progression or therapeutic resistance. Commercial availability of TCEANC2 antibodies facilitates exploration of its functional significance and interactions within transcriptional networks. However, limited literature and functional data underscore the need for further investigation to elucidate its precise mechanisms and pathophysiological relevance.

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