| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/300 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | C21orf95 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human CYYR1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于CYYR1抗体的假设性参考文献示例(请注意，这些文献为模拟示例，实际引用需核实真实来源)：
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1. **"Development of a specific monoclonal antibody for CYYR1 and its application in gastric cancer research"**
*作者：Wang X, et al. (2020)*
摘要：研究开发了一种针对CYYR1蛋白的单克隆抗体，通过免疫组化验证其在胃癌组织中的高表达，并探讨其与患者预后的相关性。
2. **"CYYR1 interacts with EGFR signaling pathway: Evidence from co-immunoprecipitation using anti-CYYR1 antibody"**
*作者：Kim S, et al. (2018)*
摘要：利用CYYR1抗体进行免疫共沉淀实验，发现CYYR1与EGFR通路蛋白存在相互作用，提示其在细胞增殖调控中的潜在作用。
3. **"A novel polyclonal antibody detects CYYR1 expression in murine brain development"**
*作者：Garcia R, et al. (2019)*
摘要：报道了一种多克隆抗体的制备，用于检测CYYR1在小鼠脑发育中的时空表达模式，揭示其与神经突触形成的关联。
4. **"CYYR1 as a biomarker in hepatocellular carcinoma: Validation by antibody-based assays"**
*作者：Liu Y, et al. (2021)*
摘要：通过Western blot和免疫荧光技术，验证CYYR1在肝细胞癌中的特异性表达，提出其作为诊断标志物的可能性。
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如需真实文献，建议通过PubMed或Google Scholar检索关键词“CYYR1 antibody”或“CYYR1 immunohistochemistry”获取最新研究。
The CYYR1 (Cysteine and Tyrosine-Rich 1) antibody is a research tool designed to target the CYYR1 protein, a relatively understudied molecule encoded by the *CYYR1* gene located on human chromosome 21. CYYR1 contains multiple cysteine and tyrosine residues, suggesting potential roles in redox regulation, protein interactions, or signaling pathways. While its precise biological function remains unclear, studies link CYYR1 to cellular processes such as adhesion, migration, and tumorigenesis. Elevated CYYR1 expression has been observed in certain cancers, including glioblastoma and colorectal cancer, implicating it as a potential biomarker or therapeutic target.
The CYYR1 antibody is primarily used in basic research to detect and quantify CYYR1 protein levels via techniques like Western blotting, immunohistochemistry, or immunofluorescence. Its development aids in mapping CYYR1's tissue distribution, subcellular localization, and interaction partners. However, commercial availability is limited, and validation data (e.g., knockout controls, specificity assays) are often sparse due to the protein’s novelty. Researchers emphasize the need for further characterization of CYYR1’s molecular mechanisms and pathological relevance. Current applications focus on exploring its involvement in cancer progression, neural development, or diseases linked to chromosome 21. such as Down syndrome. As interest grows, robust CYYR1 antibodies could accelerate functional studies and translational investigations.
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