| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | GDE3; OBDPF |
| WB Predicted band size | 62 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human GDPD2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于GDPD2抗体的3篇参考文献及其摘要内容：
1. **文献名称**：*GDPD2 Enhances Tumorigenesis and Metastasis by Promoting Wnt/β-Catenin Pathway in Gastric Cancer*
**作者**：Li Y, Zhang H, et al.
**摘要**：该研究探讨了GDPD2在胃癌中的功能，发现其通过激活Wnt/β-catenin信号通路促进肿瘤进展。研究中使用了特异性GDPD2抗体进行免疫组化和Western blot分析，证实其在胃癌组织中高表达并与不良预后相关。
2. **文献名称**：*Characterization of GDPD2 as a Potential Biomarker in Colorectal Cancer via Proteomic Profiling*
**作者**：Wang X, Chen J, et al.
**摘要**：通过蛋白质组学筛选，研究者鉴定GDPD2为结直肠癌潜在生物标志物。利用商业化GDPD2抗体进行组织微阵列分析，结果显示GDPD2在癌组织中显著上调，并与转移能力相关，提示其可作为治疗靶点。
3. **文献名称**：*GDPD2 Regulates Lipid Metabolism and Promotes Hepatocellular Carcinoma Proliferation*
**作者**：Liu S, Zheng Y, et al.
**摘要**：本研究揭示了GDPD2通过调控脂质代谢促进肝癌细胞增殖的机制。通过免疫沉淀(IP)和免疫荧光技术(使用GDPD2抗体)，证实GDPD2与脂代谢关键酶相互作用，影响肿瘤微环境中的脂质积累。
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**备注**：GDPD2相关研究相对较少，上述文献为假设性示例，实际应用中需根据具体研究领域(如癌症、代谢疾病等)进一步检索。建议通过PubMed或Web of Science以“GDPD2 antibody”或“GDPD2 function”为关键词获取最新文献。
The GDPD2 (Glycerophosphodiester Phosphodiesterase Domain-Containing Protein 2) antibody is a tool used to study the GDPD2 protein, which belongs to the glycerophosphodiester phosphodiesterase (GDPD) family. This enzyme hydrolyzes glycerophosphodiesters to produce glycerol phosphate and alcohols, playing a role in lipid metabolism and cellular signaling. GDPD2 is implicated in maintaining membrane homeostasis and regulating bioactive lipid mediators, such as lysophosphatidic acid (LPA), which influence cell proliferation, differentiation, and apoptosis.
Research on GDPD2 has linked it to metabolic disorders, cancer, and immune regulation. For instance, altered GDPD2 expression has been observed in certain tumors, suggesting its potential as a biomarker or therapeutic target. The GDPD2 antibody enables detection and quantification of the protein in tissues or cell lines via techniques like Western blot, immunohistochemistry (IHC), and immunofluorescence (IF). It is critical for investigating GDPD2's physiological functions, subcellular localization, and interaction networks.
Commercial GDPD2 antibodies are typically raised in hosts like rabbits or mice using immunogenic peptide sequences. Validation includes specificity tests (knockout controls) and application-specific performance checks. Despite its niche focus, this antibody supports broader studies in lipidomics, cancer biology, and metabolic disease mechanisms.
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