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Rabbit Polyclonal RPS7 Antibody

  • 中文名: RPS7抗体
  • 别    名: S7; eS7; DBA8
货号: IPDX10593
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/50-1/100 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/5000-1/10000 Human,Mouse,Rat

产品详情

参考文献

以下是3篇与RPS7抗体相关的文献示例(内容基于虚构情景模拟,实际文献需通过学术数据库验证):

1. **文献名称**: RPS7 modulates p53 activity in colorectal cancer progression

**作者**: Chen L, et al.

**摘要**: 研究利用RPS7抗体(CST公司,货号#XXXX)通过Western blot和免疫组化技术,发现RPS7过表达通过抑制p53通路促进结直肠癌细胞转移,揭示其作为癌症治疗靶点的潜力。

2. **文献名称**: RPS7 interacts with HIV-1 Rev protein to regulate viral replication

**作者**: Gupta S, et al.

**摘要**: 通过免疫共沉淀(使用Abcam抗RPS7抗体,abXXXX)和siRNA敲低实验,证明RPS7与HIV-1 Rev蛋白结合并调控病毒RNA核输出,为抗病毒治疗提供新方向。

3. **文献名称**: Ribosomal protein S7 deficiency links to neurodegeneration via mTOR pathway

**作者**: Müller T, et al.

**摘要**: 在小鼠模型中利用RPS7抗体(Sigma-Aldrich,SABXXXX)进行免疫荧光染色,发现神经元特异性RPS7缺失导致mTOR信号异常,引发帕金森样病理特征。

4. **文献名称**: Antibody validation for RPS7 in autoimmune disease profiling

**作者**: Kim J, et al.

**摘要**: 系统性验证多品牌RPS7抗体的特异性,通过CRISPR基因敲除细胞系证明某品牌抗体假阳性问题,强调抗体选择对类风湿关节炎患者样本分析的重要性。

(注:以上为模拟案例,实际文献需通过PubMed/Google Scholar以关键词“RPS7 antibody”、“ribosomal protein S7 antibody”配合“western blot/immunoprecipitation”等实验方法筛选)

背景信息

The RPS7 antibody is a research tool targeting Ribosomal Protein S7 (RPS7), a critical component of the 40S ribosomal subunit involved in protein synthesis. RPS7 binds to 18S rRNA during ribosome assembly and plays roles beyond translation, including DNA repair, apoptosis, and cell cycle regulation. Studies link RPS7 dysregulation to diseases such as cancer, where it may act as an oncogene or tumor suppressor depending on context, and neurodegenerative disorders. The antibody is widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to investigate RPS7's expression, localization, and interactions. Its specificity is often validated using knockout models or siRNA silencing. Research utilizing RPS7 antibodies has advanced understanding of ribosomopathies, viral infections that hijack ribosomal functions, and cellular stress responses. Both polyclonal and monoclonal variants exist, with selection depending on experimental needs. As ribosome-related pathways gain attention in therapeutic development, RPS7 antibodies remain vital for elucidating molecular mechanisms in both physiological and pathological states.

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