首页 / 产品 / 抗体 / 一抗

Rabbit Polyclonal HOXD1 Antibody

  • 中文名: HOXD1抗体
  • 别    名: HOX4; HOX4G; Hox-4.7
货号: IPDX12795
Price: ¥1180
数量:
大包装询价

验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/25-1/100 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/5000-1/10000 Human,Mouse,Rat

产品详情

AliasesHOX4; HOX4G; Hox-4.7
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human HOXD1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

参考文献

以下是3篇关于HOXD1抗体的模拟参考文献(基于公开研究领域知识,非真实存在的文献):

---

1. **文献名称**: *HOXD1 Antibody Validation in Colorectal Cancer Biomarker Screening*

**作者**: Smith J, et al.

**摘要**: 研究验证了HOXD1抗体在结直肠癌组织中的特异性,发现HOXD1蛋白高表达与肿瘤侵袭性相关,提示其作为预后标志物的潜力。

---

2. **文献名称**: *Developmental Role of HOXD1: Antibody-Based Localization in Murine Embryogenesis*

**作者**: Lee S, et al.

**摘要**: 使用HOXD1抗体进行小鼠胚胎免疫组化分析,揭示了HOXD1在肢体发育和神经管形成中的时空表达模式,支持其在形态发生中的调控作用。

---

3. **文献名称**: *HOXD1 Antibody Cross-Reactivity Analysis Across HOX Family Members*

**作者**: Garcia R, et al.

**摘要**: 评估了HOXD1抗体与其他HOX蛋白(如HOXA1、HOXC1)的交叉反应性,确认其特异性可用于精准检测HOXD1.避免同源蛋白干扰实验结论。

---

**注**:以上文献为模拟生成,真实研究需通过PubMed、Google Scholar等平台检索关键词(如"HOXD1 antibody specificity"或"HOXD1 functional analysis")获取。

背景信息

The HOXD1 antibody is a research tool designed to detect HOXD1. a protein encoded by the HOXD1 gene within the Homeobox (HOX) gene family. HOX genes play critical roles in embryonic development, particularly in establishing body segmentation and axial patterning. HOXD1. located on chromosome 2 (2q31.1), belongs to the HOXD cluster (paralog groups 1-13) and functions as a transcription factor regulating gene expression during morphogenesis. It contains a conserved 60-amino acid homeodomain that binds DNA to control developmental pathways. Studies link HOXD1 to limb development, neural tube formation, and organogenesis. Dysregulation of HOXD1 is implicated in cancers (e.g., breast, colorectal) and congenital disorders, suggesting roles in cell proliferation and differentiation. HOXD1 antibodies (polyclonal/monoclonal) are used in techniques like Western blot, immunohistochemistry, and immunofluorescence to study protein localization, expression levels, and interactions in tissues/cells. Their specificity is validated through knockout controls or peptide blocking. Research applications focus on developmental biology, oncogenesis, and regenerative medicine, with some exploring HOXD1's crosstalk with signaling pathways (e.g., Wnt, BMP). Challenges include cross-reactivity with homologous HOX proteins, necessitating careful antibody validation for experimental accuracy.

客户数据及评论

折叠内容

大包装询价

×