关键信息
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基因名
HINT1
- 应用
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别名
HINT1;HINT;PKCI1;PRKCNH1;Adenosine 5'-monophosphoramidase HINT1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P49773
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表达区间
2-126aa
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氨基酸序列
ADEIAKAQV ARPGGDTIFG KIIRKEIPAK IIFEDDRCLA FHDISPQAPT HFLVIPKKHI SQISVAEDDD ESLLGHLMIV GKKCAADLGL NKGYRMVVNE GSDGGQSVYH VHLHVLGGRQ MHWPPG
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
HINT1, or Hepatitis A Virus Interacting Protein 1, is a crucial protein involved in various cellular processes, including cell signaling and apoptotic regulation. Research on HINT1 has gained attention due to its role in cancer biology and neurodegenerative diseases. It was initially identified as a protein that interacts with the hepatitis A virus, but further studies revealed its significance in modulating cellular responses to stress and inflammation. HINT1 has been implicated in the regulation of tumor suppressor pathways, making it a potential target for cancer therapy. Additionally, it has shown protective functions in neural cells, suggesting that it may play a role in preventing neurodegeneration. Understanding the structure and function of HINT1 can provide insights into its biological roles and therapeutic potential. Recombinant HINT1 protein production has facilitated investigations into its interactions, mechanisms of action, and potential applications in drug development. As research progresses, HINT1 may emerge as a significant biomarker and therapeutic target in various diseases, enhancing our comprehension of its complex biological functions.
